Results 311 to 320 of about 107,657 (326)

Novel positive allosteric modulators of GABA(A) receptors

Drugs of the Future, 2001
null Sigel, E., null Dodd, R.H.
openaire   +1 more source

Functional properties and mechanism of action of PPTQ, an allosteric agonist and low nanomolar positive allosteric modulator at GABAA receptors

Biochemical Pharmacology, 2018
Nawid Madjroh, Christoffer Bundgaard, Anders A Jensen   +2 more
exaly  

β-Arrestin-Biased Allosteric Modulator of NTSR1 Selectively Attenuates Addictive Behaviors

Cell, 2020
Lauren M Slosky, Yushi Bai, Krisztián Tóth   +2 more
exaly  

Effect of the Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor 2 AZD8529 on Incubation of Methamphetamine Craving After Prolonged Voluntary Abstinence in a Rat Model

Biological Psychiatry, 2015
Daniele Caprioli, Marco Venniro, Xuan Li   +2 more
exaly  

Preclinical profile of a novel metabotropic glutamate receptor 5 positive allosteric modulator

European Journal of Pharmacology, 2011
Jeffrey S Smith, Patricia Schroeder, Minli Zhang   +2 more
exaly  

New Trends in the Development of Positive Allosteric Modulators of AMPA Receptors

Current Medicinal Chemistry-Central Nervous System Agents, 2004
Graindorge, E., Francotte, Pierre, Boverie, S., De Tullio, Pascal, Pirotte, Bernard   +4 more
openaire   +2 more sources

An orally bioavailable positive allosteric modulator of the mGlu4 receptor with efficacy in an animal model of motor dysfunction

Bioorganic and Medicinal Chemistry Letters, 2010
Stephen P East, Christian Eickmeier, Boris Ferger   +2 more
exaly  

The drug candidate, ADX71441, is a novel, potent and selective positive allosteric modulator of the GABAB receptor with a potential for treatment of anxiety, pain and spasticity

Neuropharmacology, 2017
M. Kalinichev, Françoise Girard, H. Haddouk, M. Rouillier, E. Riguet, I. Royer-Urios, V. Mutel, Robert Lütjens, S. Poli   +8 more
semanticscholar   +1 more source

Novel positive allosteric modulator of AMPA-receptors based on tricyclic scaffold

, 2018
M. Lavrov, D. Karlov, V. Palyulin, V. Grigoriev, V. Zamoyski, G. Brkich, N. Pyatigorskaya, Maxim E. Zapolskiy   +7 more
semanticscholar   +1 more source

Efficient One-Pot Synthesis of the GABAB Positive Allosteric Modulator (R,S)-5,7-Di-tert-butyl-3-hydroxy-3-trifluoromethyl-3H-benzofuran-2-one

Synthetic Communications, 2008
Roger D Norcross
exaly