Results 321 to 326 of about 107,657 (326)

Identification and Characterization of the First Selective Y4 Receptor Positive Allosteric Modulator.

Journal of Medicinal Chemistry, 2017
M. Schubert, Jan Stichel, Yu Du, I. Tough, Gregory Sliwoski, J. Meiler, H. Cox, C. Weaver, A. Beck‐Sickinger   +8 more
semanticscholar   +1 more source

Discovery of a selective M4 positive allosteric modulator based on the 3-amino-thieno[2,3-b]pyridine-2-carboxamide scaffold: Development of ML253, a potent and brain penetrant compound that is active in a preclinical model of schizophrenia

Bioorganic and Medicinal Chemistry Letters, 2013
Thomas M Bridges, Paige N Vinson, Thomas J Utley   +2 more
exaly  

Discovery of a potent and brain penetrant mGluR5 positive allosteric modulator

Bioorganic and Medicinal Chemistry Letters, 2009
exaly  

Discovery of N-(4-methoxy-7-methylbenzo[d]thiazol-2-yl)isonicatinamide, ML293, as a novel, selective and brain penetrant positive allosteric modulator of the muscarinic 4 (M4) receptor

Bioorganic and Medicinal Chemistry Letters, 2012
Paige N Vinson, Douglas J Sheffler, Atin Lamsal   +2 more
exaly  

Therapeutic effects of metabotropic glutamate receptor 5 positive allosteric modulator CDPPB on phencyclidine‐induced cognitive deficits in mice

Fundamental and Clinical Pharmacology, 2013
Mao Horio, Yuko Fujita
exaly  

Discovery of a Positive Allosteric Modulator of the Thyrotropin Receptor: Potentiation of Thyrotropin-Mediated Preosteoblast Differentiation In Vitro

Journal of Pharmacology and Experimental Therapeutics, 2018
S. Neumann, E. Eliseeva, Alisa Boutin, E. Barnaeva, M. Ferrer, Noel Southall, David D. Kim, Xin Hu, S. Morgan, J. Marugan, M. Gershengorn   +10 more
semanticscholar   +1 more source