Results 61 to 70 of about 266,039 (331)

A discrete districting plan

open access: yes, 2019
The outcome of elections is strongly dependent on the districting choices, making thus possible (and frequent) the gerrymandering phenomenon, i.e.\ politicians suitably changing the shape of electoral districts in order to win the forthcoming elections ...
Saracco, Alberto, Saracco, Giorgio
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

An Evaluation Framework for Sustainable Plus Energy Neighbourhoods: Moving Beyond the Traditional Building Energy Assessment

open access: yesEnergies, 2021
There are international activities and on-going initiatives, particularly at the European level, to define what Positive Energy Districts should be, as the driving concept for the urban transition to a sustainable future. The first objective of the paper
Jaume Salom   +15 more
doaj   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Positive energy districts and energy communities: how living labs create value

open access: yesBuildings & Cities
Urban living labs (ULLs) are experimental governance mechanisms accelerating sustainability transitions in the built environment, yet their governance implications and systemic impact are often under-examined.
Elena Malakhatka   +3 more
doaj   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

INTERACT - Integration of innovative technologies of PEDs into a holistic architecture

open access: yesActa Polytechnica CTU Proceedings, 2022
INTERACT is an international research and innovation project which boosts the emergence of Energy Communities as one crucial building block to achieve Positive Energy Districts. It is designing an optimal organization and structure for Energy Communities
Helmut Bruckner   +3 more
doaj   +1 more source

Assessment of technical and socioeconomical feeding practices in semiarid and arid Areas in north India (Haryana), and implications for dairy rural development [PDF]

open access: yes, 2008
To satisfy Indian consumers¿ rising demand for milk products, Indian breeders will have to boost their production rapidly, especially through improved feeding practices.
Alary, Véronique   +4 more
core   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Urban Wind as a Pathway to Positive Energy Districts

open access: yesEnergies
The increasing demand for decarbonized urban environments has intensified interest in integrating renewable energy systems within cities. This review investigates the potential of urban wind energy as a promising technology in the development of Positive
Krzysztof Sornek   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy