Results 31 to 40 of about 847,425 (305)
, 2016 We adopted 2 theoretical perspectives (goal achievement and information value) to determine the conditions under which people prefer to receive positive or negative feedback information.
Tseng, Chung-Hui
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Frontiers in PhysiologySince being articulated by Claude Bernard, and ultimately named by Walter Cannon, the theory of Homeostasis has been a conceptual and practical bedrock of physiology and medicine.
Nelson D. Horseman
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Biology Open, 2022 Many human birth defects and neurodevelopmental disorders are caused by loss-of-function mutations in a single copy of transcription factor (TF) and chromatin regulator genes.
Roman Zug
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Is no praise good praise? Effects of positive feedback on children’s and university students’ responses to subsequent failures. [PDF]
, 2011 Background: According to Dweck and colleagues (e.g., Kamins & Dweck, 1999; Mueller & Dweck, 1986), praise can be delivered using person (“you are clever”) or process terms (“you worked hard”).
Karen Douglas +5 more
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Why all MODY variants in transcription factor genes are dominantly inherited
Frontiers in GeneticsMaturity-onset diabetes of the young (MODY) is an autosomal dominant form of monogenic diabetes, frequently caused by heterozygous loss-of-function variants in transcription factor (TF) genes. Why are MODY variants in TF genes dominantly inherited?
Roman Zug, Roman Zug
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Molecular Therapy: Methods & Clinical Development, 2022 VP64 is the smallest transactivation domain that can be packaged together with the sgRNA into a single adeno-associated virus (AAV) vector. However, VP64-based CRISPRa often exerts modest activation to the target gene when only one sgRNA is used. Herein,
Cia-Hin Lau +3 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
When overconfident traders meet feedback traders [PDF]
, 2011 In this paper, we develop a model in which overconfident market participants and rational speculators trade against trend-chasers. We exhibit the unique linear equilibrium and assess the quality of prices according to the proportion of the different ...
Boco, Hervé +2 more
core
Mean field analysis of a spatial stochastic model of a gene regulatory network
, 2015 A gene regulatory network may be defined as a collection of DNA segments which interact with each other indirectly through their RNA and protein products.
Murray, P. J. +3 more
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