Results 61 to 70 of about 6,596,021 (288)
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Garcia Conesa, Maria-Teresa +2 more
core +2 more sources
Positive Feedbacks of Coagulation [PDF]
Tissue factor (TF), the initiator of coagulation, continuously circulates in the plasma, and the clotting system “idles,” generating very low levels of active clotting enzymes, clotting products, and by-products. Given the enormous amplification potential of the clotting cascade, rigorous control is required to ensure that such low-level stimulation ...
Jolyon, Jesty, Edward, Beltrami
openaire +2 more sources
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Stability of positive-position feedback controllers with low-frequency restrictions [PDF]
Peer ...
Aphale, Sumeet Sunil, Pereira, Emiliano
core +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Four-wave mixing on thermal nonlinearity in a scheme with positive feedback [PDF]
The influence of feedback for both signal and object waves on the amplitude reflection coefficient of a four-wave radiation converter on thermal nonlinearity has been considered.
Aleksandr Akimov +2 more
doaj +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Positive feedback control of Rayleigh-Bénard convection [PDF]
We consider the problem of active feedback control of rbc via shadowgraphic measurement. Our theoretical studies show, that when the feedback control is positive, i.e.
Bertozzi, Andrea L. +2 more
core +1 more source
This paper presents an integrated operational amplifier (OPAMP) consisting of only n-type metal oxide thin-film transistors. In addition to using positive feedback in the input differential pair, a transconductance-enhancement topology is applied to ...
Zhuo-Jia Chen +9 more
doaj +1 more source

