Results 141 to 150 of about 335,000 (300)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Jurnal Manajemen dan Bisnis KreatifThe retail industry will face systemic challenges, one of which is a labor shortage. Generation Z, with work expectations different from previous generations, presents a new challenge for companies in attracting, developing, and retaining talent.
Kezia Safanya Khairunnisa +2 more
doaj +3 more sources
Irreducible and periodic positive maps
, 2009 We extend the notions of irreducibility and periodicity of a stochastic matrix to a unital positive linear map $\Phi$ on a finite-dimensional C*-algebra A and discuss the non-commutative version of the Perron-Frobenius theorem. As an example, positive
Pellicer, Rely +4 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Self-adjoint square roots of positive self-adjoint bounded linear operators
A corollary of the main theorem presented in this note is a generalisation of the well-known result that a self-adjoint square root of a positive self-adjoint compact linear map in a Hilbert space is itself a compact linear map.
Stuart, C. A.
core +1 more source
Dilations and Hahn Decompositions for Linear Maps
, 1981 Suppose is a C*-algebra and H is a Hilbert space. Let denote the set of completely positive maps from into the set B(H) of (bounded linear) operators on H.
D. W. Hadwin
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Linear maps between certain nonseparable 𝐶*-algebras
, 1984 There exists a noninjective commutative C ∗ {C^ * } -algebra A A such that every bounded linear map of any C ∗ {C^ * } -algebra ...
Tadasi Huruya
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source