Results 111 to 120 of about 221,597 (311)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Positive Functionals on General Operator Algebras
, 2000 We show that any weakly closed algebra of bounded operators acting on a Banach space and different from the algebra of all bounded operators admits positive vector-functionals continuous in the essential operator ...
Lomonosov, V.
core +1 more source
Further Improved Weighted Arithmetic-Geometric Operator Mean Inequalities
Mathematics, 2019 The main purpose of this paper is to present some weighted arithmetic-geometric operator mean inequalities. These inequalities are refinements and generalizations of the corresponding results.
Jianming Xue, Xingkai Hu
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Continuations of Hermitian indefinite functions and corresponding canonical systems : an example
, 2004 M. G. Krein established a close connection between the continuation problem of positive definite functions from a finite interval to the real axis and the inverse spectral problem for differential operators.
Langer, M. +5 more
core
Positive-P and Wigner representations for quantum-optical systems with nonorthogonal modes
, 2002 Positive-P and Wigner representations for quantum-optical systems with nonorthogonal modes were discussed. The operator correspondences connecting the underlying density operator with the corresponding Fokker-Planck equations were developed.
H. Ritsch (3986231) +3 more
core +1 more source
Positive decaying solutions to BVPs with mean curvature operator [PDF]
, 2017 A boundary value problem on the whole half-closed interval [1,∞) , associated to diff erential equations with the Euclidean mean curvature operator or with the Minkowski mean curvature operator is here considered.
Matucci, Serena +2 more
core +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Positive operator bimeasures and a noncommutative generalization
, 1996 For C*-algebras A and B and a Hilbert space H, a class of bilinear maps Φ: A× B → L(H), analogous to completely positive linear maps, is studied. A Stinespring type representation theorem is proved, and in case A and B are commutative, the class is shown
Ylinen, Kari
core
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source