Results 121 to 130 of about 221,597 (311)
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Existence of positive solutions for non local p-Laplacian thermistor problems on time scales
, 2007 We make use of the Guo-Krasnoselskii fixed point theorem on cones to prove existence of positive solutions to a non local p-Laplacian boundary value problem on time scales arising in many applications. © 2007 Victoria University.
Ammi, M.R.S., Torres, D.F.M.
core
Positive Lyapunov exponent of discrete analytic Jacobi operator
Electronic Journal of Differential Equations, 2017 In this article, we study the Lyapunov exponent of discrete analytic Jacobi operator with a family of some mappings on the torus. By applying the theory of subharmonic functions, we prove that the Lyapunov exponent is positive, if the coupling number ...
Kai Tao
doaj
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Unital completely positive maps and their operator systems
, 2023 A vector subspace $\cls$ of $\IM_n(\IC)$ is called unital operator system if $x \in \cls$ if and only if $x^* \in \cls$ and the identity operator $I_n \in \cls$, where $n$ is any fixed positive integer. Let $C^*(\cls)$ be the $C^*$ sub-algebra of $\IM_n(\
Mohari, Anilesh
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FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Convergence of positive operator semigroups
, 2019 We present new conditions for semigroups of positive operators to converge strongly as time tends to infinity. Our proofs are based on a novel approach combining the well-known splitting theorem by Jacobs, de Leeuw, and Glicksberg with a purely algebraic
Glück, Jochen (Dr.) +1 more
core +1 more source
The Voronovskaya theorem for some operators of the Szasz-Mirakjan type
Le Matematiche, 1995 We give the Voronovskaya theorem for some operators of the Szasz-Mirakjan type defined in the space of functions continuous on [0,+infinity) and having the polynomial grouth at infinity. Some approximation properties of these operators are given in [2],
Lucina Rempulska, Mariola Skorupka
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