Results 91 to 100 of about 327,787 (287)
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley +1 more source
BackgroundResearch has shown that parenting style disparities have a significant impact on the mental health of college students. However, the underlying reasons behind this phenomenon have not been sufficiently explored.
Li Yang +4 more
doaj +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
In China, grandparents play a significant role in childrearing. This study aims to identify latent profiles of intergenerational parenting styles and explore their impact on grandchildren’s behavioral outcomes. A total of 1432 Chinese children (Mage = 12.
Furong Lu +4 more
doaj +1 more source
It is increasingly urgent to address issue around parenting. The family remains a fundamental loop in the wellbeing of society. I am a strong believer that healthy communities are founded on happy families, ‘happiness’ in the widest sense of the word.
Azzopardi, Andrew +1 more
openaire +1 more source
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Research Framework: Studying the impact of both parents’ parenting practices suggests that, just as the mother’s, the father’s parenting practices make a positive contribution to the child’s social adjustment.
Camille Caron +3 more
doaj
Paper presented to the Scottish Institute for Residential Child Care Annual Conference, 2009: 'Seeing the whole picture: working in partnership to enhance the lives of children looked after away from home'
Pilkington, Kevin, Burns, Claire
openaire
The importance of early parenting for later child outcomes: A study with Spanish families with children with disabilities [PDF]
Children with different disability conditions have varied developmental trajectories, which perhaps influences parent-child interaction. For these and all infants, an optimal home environment that includes good parenting and positive parent-child ...
Bersabe-Moran, Rosa Maria +6 more
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