Results 71 to 80 of about 5,058,316 (286)

Home learning environment and positive parenting on children’s learning outcomes in Afghanistan

Cogent Psychology
This study assesses whether home learning environment and positive parenting are associated with children’s literacy and numeracy. This study used cross-section quantitative data from 2152 school children aged 7–16 years from seven provinces in ...
Conrad Murendo, Zahra Azemi, Silvia Mila Arlini, Than Zaw Oo, Martin Odhiambo, Edwin Kimani, Azhari Abdul Jabar, Melissa Burgess   +7 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Investigating the Relationship between Parenting Styles and Delinquent Behavior [PDF]

, 2004
Although numerous studies have examined the connection between delinquent behavior and parenting styles in children and adolescents, limited research has been done to determine if there is an ongoing relationship between these variables in the college ...
Terry, Danielle J.
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Parenting on a low income [PDF]

, 2012
Given the negative effects of financial hardship, and the current economic climate, About Families asked what research could tell us about parenting on a low income. The full report (with references) is available at www.aboutfamilies.org.uk.
Mountney, Karen
core   +3 more sources

The impact of parenting style on malevolent creativity based on Chinese university students: a latent profile analysis

Frontiers in Psychology
IntroductionThis study investigated the association between parenting styles and malevolent creativity.MethodsIt used latent profile analysis to compare the differences in malevolent creativity between different combinations of parenting styles with an ...
Xingnan Cui, Xiang Zhang, Xiang Zhang, Hua Zhang   +3 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Positive Illusions in Parenting: Systematic Review

Psikiyatride Güncel Yaklaşımlar
Positive illusions in parenting refer to the tendency of parents to hold overly favorable beliefs about their children’s abilities, intelligence, character, or achievements, often diverging from objective reality.
Gülçin Karadeniz, Rabia Hıdırlar, İlaydanur Taşdemir   +2 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source