Results 91 to 100 of about 4,110,990 (410)

Comparison of efficiency between RMI1 and RMI2 in diagnosing ovarian malignancy [PDF]

, 2019
Background: This study was conducted in department of obstetrics and gynaecology, to know the efficiency of risk of malignancy index (RMI) to differentiate a malignant from a benign tumor and to compare the efficiency of risk of malignancy index 1 and 2 (
Kabadi, Narayan Y., Shalagar, Rashmi R.
core   +2 more sources

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

A Threshold-free Prospective Prediction Accuracy Measure for Censored Time to Event Data [PDF]

Statistics in Medicine 37(10):1671-1681, 2018, 2016
Prediction performance of a risk scoring system needs to be carefully assessed before its adoption in clinical practice. Clinical preventive care often uses risk scores to screen asymptomatic population. The primary clinical interest is to predict the risk of having an event by a pre-specified future time $t_0$.
arxiv   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

Clinical Usefulness of Cervicogram as a Primary Screening Test for Cervical Neoplasia [PDF]

, 2005
The purpose of this study is to evaluate the clinical usefulness of the cervicogram as a primary screening test for cervical neoplasia. A total of 294 women who had undergone a cervicogram and a Pap test between January and July 2003, were selected.
Ahn, Bo Sung Yoon, Burke, Campion, Coppleson, Farley, Favaheirier, Ferris, Giles, Han, Hocutt, IARC working group on evaluation of cervical cancer screening programs, Jae Hoon Kim, Jae Wook Kim, Kang, Kim, Laura, Maggi, Namgung, Orr, Parkin, Richart, Sankaranarayanan, Sherman, Singer, Soost, Stafl, Stafl, Sung Hoon Kim, Szarewski, Yong Won Park, Young Tae Kim, Yu Ri Kim   +32 more
core   +2 more sources

Poor Positive Predictive Value of Lyme Disease Serologic Testing in an Area of Low Disease Incidence.

Clinical Infectious Diseases, 2015
BACKGROUND Lyme disease is diagnosed by 2-tiered serologic testing in patients with a compatible clinical illness, but the significance of positive test results in low-prevalence regions has not been investigated.
Paul M. Lantos, J. Branda, J. Boggan, S. Chudgar, E. A. Wilson, F. Ruffin, V. Fowler, P. Auwaerter, L. Nigrovic   +8 more
semanticscholar   +1 more source

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

FEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan, Rosa Sanchez‐Alvarez, Chiho Kambara, Poojitha Rajasekar, Yuluang Wang, François Halloy, Jonathan Hall, Hans‐Jürgen Stark, Iris Martin, Petra Boukamp, Svitlana Kurinna   +10 more
wiley   +1 more source

Generalized oscillator strength for Na 3s-3p transition [PDF]

Phys Rev A Rapid Communications, vol 61, published 3 Feb, 2000, 2000
Generalized oscillator strengths (GOS's) for the Na $3s -3p$ transition have been investigated using the spin-polarized technique of the random phase approximation with exchange (RPAE) and the first Born approximation (FBA), focussing our attention on the position of the minimum.
arxiv   +1 more source

Cytoplasmic delivery of antibodies through grafting a functional single complementarity‐determining region loop

FEBS Letters, EarlyView.
We achieved cytoplasmic delivery of non‐cell‐penetrating IgGs by grafting a single functional complementarity‐determining region 1 (CDR1) from the light chain variable region (VL) of the cell‐internalizable 3D8 antibody. The engineered IgG acquired cell‐penetrating ability while maintaining antigen affinity, highlighting CDR1 grafting as a promising ...
Yerin Jeon, Juho Choi, Youngin Roh, Eunbin Lee, Luigie Villamante, Myung‐Hee Kwon   +5 more
wiley   +1 more source

Test de activación de basófilos en el diagnóstico de alergia a medicamentos [PDF]

, 2003
In this paper we study the reliability of the basophil activation test (BAT) in the "in-vitro" diagnosis of allergy to betalactams and to metamizol, and the sensitivity and specificity of the technique are analyzed.
Caballero, M.R. (M.R.), Dieguez, I. (I.), Gamboa, P.M. (P. M.), Garcia, M.C. (M. C.), Sanz, M.L. (María Luisa)   +4 more
core   +1 more source