Results 91 to 100 of about 4,116,426 (324)

The importance of screening in children who snore [PDF]

, 2019
It is important to screen for OSAS in children who snore, as early treatment of OSAS can prevent neurocognitive, behavioural, cardiovascular and metabolic consequences.
Evangelisti, M., Villa, Mp
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Positive Predictive Value of ICD-10 Diagnosis Codes for COVID-19

Clinical Epidemiology, 2021
Jacob Bodilsen,1 Steffen Leth,2,3 Stig Lønberg Nielsen,4,5 Jon Gitz Holler,6 Thomas Benfield,7 Lars Haukali Omland8 1Department of Infectious Diseases, Aalborg University Hospital, Aalborg, Denmark; 2Department of Infectious Diseases, Aarhus ...
Bodilsen J, Leth S, Nielsen SL, Holler JG, Benfield T, Omland LH   +5 more
doaj  

The incidence of liver injury in Uyghur patients treated for TB in Xinjiang Uyghur autonomous region, China, and its association with hepatic enzyme polymorphisms nat2, cyp2e1, gstm1 and gstt1. [PDF]

, 2014
BACKGROUND AND OBJECTIVE: Of three first-line anti-tuberculosis (anti-TB) drugs, isoniazid is most commonly associated with hepatotoxicity. Differences in INH-induced toxicity have been attributed to genetic variability at several loci, NAT2, CYP2E1 ...
A Tostmann, Atikaimu Wubuli, B Roy, B Roy, C Benichou, Corinne Merle, D Yee, DL Zhu, DS Huang, DW Hein, H Devarbhavi, HG Xie, HJ Cho, HJ De Rosa, HR An, HR An, I Vieira, J Meyer D, JH Wang, Jiayi Gu, Jinfeng Ma, JJ Saukkonen, JN Hirschhorn, JN Pande, JR Mitchell, JR Mitchell, Lei Yang, LG Possuelo, Long Ma, M Dossing, M Guo, M Guo, M Ingelman-Sundberg, M Ohno, M Runge-Morris, Mark Patrick Nicol, Mingqin Cao, N Vuilleumier, Paul Milligan, PD Bose, PD Roy, Qian Wang, Qian Wang, R Shakya, RC Strange, RL Teixeira, S Chatterjee, S Huang Y, S Russmann, S Sunahara, S Yamada, SH Kim, SH Kim, SK Sharma, SW Lee, SW Tang, T Mohri, T Sotsuka, T Wang, T Wang, T Yamamoto, V Leiro, Wei Liu, Weidong Wu, WJ Burman, WM Lee, WW Yew, Xia Zhu, Xiumei Xin, Xuemei Yao, XZ Lv, Y Chen, Yang Xiang, Ying Mao, YM Wu, Yongguang Li, YS Huang, YS Huang, YS Huang, YS Huang   +79 more
core   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Positive predictive value of the infant respiratory distress syndrome diagnosis in the Danish National Patient Registry

Clinical Epidemiology, 2013
Sandra Kruchov Thygesen, Morten Olsen, Christian Fynbo ChristiansenDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, DenmarkBackground: Infant respiratory distress syndrome (IRDS) is the most common respiratory disease in preterm ...
Thygesen SK, Olsen M, Christiansen CF
doaj  

Automated electroencephalographic discontinuity in cooled newborns predicts cerebral MRI and neurodevelopmental outcome [PDF]

, 2016
BACKGROUND AND HYPOTHESIS: Prolonged electroencephalographic (EEG) discontinuity has been associated with poor neurodevelopmental outcomes after perinatal asphyxia but its predictive value in the era of therapeutic hypothermia (TH) is unknown.
Boardman, James P, Chisholm, Philippa, Clarke, Paul, Dunne, Jonathan M, Kapellou, Olga, Shah, Divyen K, Wertheim, David   +6 more
core   +3 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Positive predictive value of the International Classification of Diseases, 10th edition diagnosis codes for anemia caused by bleeding in the Danish National Registry of Patients

Clinical Epidemiology, 2012
Jihen Zalfani, Trine Frøslev, Morten Olsen, Inès Ben Ghezala, Henrik Gammelager, Johan FB Arendt, Rune ErichsenDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, DenmarkObjective: Valid data on anemia caused by
Zalfani J, Frøslev T, Olsen M, Ben Ghezala I, Gammelager H, Arendt JFB, Erichsen R   +6 more
doaj  

Noninvasive prenatal testing in the general obstetric population: clinical performance and counseling considerations in over 85000 cases

Репродуктивная эндокринология, 2017
The article contains the results of the research, which set two main goals. The first is the determination of the actual indicators of the effectiveness of noninvasive prenatal studies and the development of counseling tools about the predictability of a
P. A. Taneja, H. L. Snyder, E. de Feo, K. M. Kruglyak   +3 more
doaj   +1 more source