Ludvig Öhman, Magdalena Johansson, Jan-Håkan Jansson, Marcus Lind, Lars Johansson Department of Public Health and Clinical Medicine, Skellefteå Research Unit, Umeå University, Umeå, Västerbotten, Sweden Purpose: To ...
Öhman L +4 more
doaj
The Positive Predictive Value of Pediatric Stroke Diagnoses in Administrative Data: A Retrospective Validation Study. [PDF]
Bindslev JB +5 more
europepmc +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Positive predictive value metrics for multicancer detection tests. [PDF]
Pinsky PF +3 more
europepmc +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Positive predictive value of symptoms for early-onset colorectal cancer. [PDF]
Chubak J +11 more
europepmc +1 more source
Positive Predictive Value of ICD-10 Codes to Identify Acute Suicidal and Self Harm Behaviors. [PDF]
Johnson JA +10 more
europepmc +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Evidence Based Medicine; Positive and negative predictive values of diagnostic tests
Saeed Safari, Alireza Baratloo
doaj
Sensitivity and positive predictive value of diagnosis codes for acute kidney injury in Denmark. [PDF]
Høyer S +4 more
europepmc +1 more source

