Results 121 to 130 of about 791,044 (254)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

International classification of diseases codes have low positive predictive value for neonatal morbidities. [PDF]

open access: yesJ Perinatol
Hendrickson JE   +19 more
europepmc   +1 more source

Positive Predictive Value of Non-Traumatic Bleeding Diagnoses in the Danish National Patient Register. [PDF]

open access: yesClin Epidemiol, 2023
Thaarup M   +6 more
europepmc   +1 more source

Comment on the Positive Predictive Value [PDF]

open access: yesDeutsches Ärzteblatt international, 2011
openaire   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Part 2: Positive and negative predictive values of diagnostic tests

open access: yesEmergency, 2015
Saeed Safari   +3 more
doaj  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Positive Predictive Value of Tissue Transglutaminase IgA for Celiac Disease. [PDF]

open access: yesPediatrics
Chang D   +22 more
europepmc   +1 more source

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