Results 141 to 150 of about 4,116,426 (324)

Validation of Postsurgical Venous Thromboembolism Diagnoses of Patients Undergoing Lower Limb Orthopedic Surgery in the Danish National Patient Registry

Clinical Epidemiology, 2022
Josephine Galsklint,1 Søren Kold,2,3 Søren Risom Kristensen,1,2 Marianne Tang Severinsen,2,4 Inger Lise Gade2,4,5 1Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark; 2Department of Clinical Medicine, Aalborg University ...
Galsklint J, Kold S, Kristensen SR, Severinsen MT, Gade IL   +4 more
doaj  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Intracerebral hemorrhage: positive predictive value of diagnosis codes in two nationwide Danish registries

Clinical Epidemiology, 2018
Stine Munk Hald,1,2 Christine Kring Sloth,1,2 Sabine Morris Hey,1,2 Charlotte Madsen,1 Nina Nguyen,3 Luis Alberto García Rodríguez,4 Rustam Al-Shahi Salman,5 Sören Möller,2,6 Frantz Rom Poulsen,7 Anton Pottegård,8 David ...
Hald SM, Kring Sloth C, Hey SM, Madsen C, Nguyen N, García Rodríguez LA, Al-Shahi Salman R, Möller S, Poulsen FR, Pottegård A, Gaist D   +10 more
doaj  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Positive predictive value of the ICD-10 hospital diagnosis of pleural empyema in the Danish National Registry of Patients

Clinical Epidemiology, 2011
Mette Søgaard1,2, Jette Brommann Kornum2, Henrik Carl Schønheyder1, Reimar Wernich Thomsen21Department of Clinical Microbiology, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark; 2Department of Clinical Epidemiology ...
Mette Søgaard, Jette Brommann Kornum, Henrik Carl Schønheyder, et al   +3 more
doaj  

Comparison of Calcofluor White M2R fluorescence and modified Gram chromotrope Kinyoun staining methods for the detection of microsporidial spores from stool samples [PDF]

, 2013
Routine diagnosis of intestinal microsporidiosis in clinical diagnostic laboratories relies mostly on detection of microsporidial spores via special staining and microscopic techniques.
Abdul Rahman, Eni Juraida, Hamat, Rukman Awang, Ithnin, Nur Raihana, M. S., Fatmah, M., Norhayati, Osman, Malina   +5 more
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Positive predictive value of the diagnosis coding for vitamin B12 deficiency anemia in the Danish National Patient Register

Clinical Epidemiology, 2012
Inès Ben Ghezala, Johan Frederik Berg Arendt, Rune Erichsen, Jihen Zalfani, Henrik Gammelager, Trine Frøslev, Morten OlsenDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, DenmarkPurpose: The aim of this ...
Ben Ghezala I, Arendt JF, Erichsen R, Zalfani J, Gammelager H, Frøslev T, Olsen M   +6 more
doaj  

Comparison of Tan Thiam Hok, Ziehl Neelsen and Fluorochrome as Acid-Fast Bacilli Staining Methods in Sputum [PDF]

, 2005
Because of its simplicity, rapidity, low cost and relatively sensitive, sputum acid-fast bacilli (AFB) smear microscopy is the primary tool for detecting pulmonary tuberculosis and follow up of therapy. This experiment is aimed to determine the
Alisyahbana, B. (Bachti), Karuniawati, A. (Anis), Melia, W. (Wia), Nilawati, S. (S), Parwati, I. (Ida), Prawoto, P. (Prawoto), Risdiyani, E. (E), Rosana, Y. (Yeva), Sudiro, T. M. (T)   +8 more
core