Molecular Oncology, EarlyView.Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley +1 more source
Evaluation of a New Recombinant K39 Rapid Diagnostic Test for Sudanese Visceral Leishmaniasis. [PDF]
, 2006 A new rK39 rapid diagnostic dipstick test (DiaMed-IT-Leish) was compared with aspiration and a direct agglutination test (DAT) for diagnosis of visceral leishmaniasis (VL) in 201 parasitologically confirmed cases, 133 endemic controls, and in 356 ...
Davidson, R N +5 more
core +1 more source
The Positive Predictive Value of Pediatric Stroke Diagnoses in Administrative Data: A Retrospective Validation Study. [PDF]
Clin Epidemiol, 2023 Bindslev JB +5 more
europepmc +1 more source
A Systematic Bias of Machine Learning Regression Models and Its Correction: an Application to Imaging-based Brain Age Prediction [PDF]
arXivMachine learning models for continuous outcomes often yield systematically biased predictions, particularly for values that largely deviate from the mean. Specifically, predictions for large-valued outcomes tend to be negatively biased (underestimating actual values), while those for small-valued outcomes are positively biased (overestimating actual ...
arxiv
Estimation of Predictive Value of a Positive Test from a Screening Test [PDF]
, 2003 Hyun Chul Shin +2 more
openalex +1 more source
Clinical significance of stratifying prostate cancer patients through specific circulating genes
Molecular Oncology, EarlyView.We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian +12 more
wiley +1 more source
Positive Predictive Value of Non-Traumatic Bleeding Diagnoses in the Danish National Patient Register. [PDF]
Clin Epidemiol, 2023 Thaarup M +6 more
europepmc +1 more source
Predicting BVD Re-emergence in Irish Cattle From Highly Imbalanced Herd-Level Data Using Machine Learning Algorithms [PDF]
arXivBovine Viral Diarrhoea (BVD) has been the focus of a successful eradication programme in Ireland, with the herd-level prevalence declining from 11.3% in 2013 to just 0.2% in 2023. As the country moves toward BVD freedom, the development of predictive models for targeted surveillance becomes increasingly important to mitigate the risk of disease re ...
arxiv
Anti-C1q antibodies in nephritis: correlation between titres and renal disease activity and positive predictive value in systemic lupus erythematosus [PDF]
, 2004 Natália Marto
openalex +1 more source
Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source