Results 41 to 50 of about 8,991,569 (289)
Existence of Positive Radial Solutions for Elliptic Systems
This article is devoted to the study of the equation \(\partial\theta/\partial t=\text{div}({\mathcal R}\nabla p_t)+f\), where \(\theta(t,x)\) is the saturation, \(\mathcal R\) is the matrix \((a_{ij})=(\rho/\mu)\kappa_{ij}\), where the \(n\times n\)-matrix \((\kappa_{ij}(x))\) describes the permeability of the medium, \(\mu\) is the viscosity of the ...
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Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
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We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
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Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
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Take the A-Metric: Interpretations of Some Known Solutions of Einstein’s Vacuum Field Equations
In this work, we present a new interpretation of the only static vacuum solution of Einstein’s field equations with planar symmetry, the Taub solution. This solution is a member of the AIII class of metrics, along with the type D Kasner solution. Various
Charles W. Robson, Marco Ornigotti
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The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
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Radial Symmetry of Positive Solutions of Nonlinear Elliptic Equations
Three results concerning the radial symmetry and asymptotic behaviour at \(x=\infty\) of positive solutions of \[ \Delta u = \varphi(\mid x\mid)u^{\lambda}, \quad x\in \mathbb{R}^n \] and \(|x|\) large are presented. Here \(\lambda>1\) and \(\varphi(r)\) is positive and continuous for \(r\) large. There are three cases which are separately analysed: (I)
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Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
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We examine the conditional regularity of the solutions of Navier-Stokes equations in the entire three-dimensional space under the assumption that the data are axially symmetric.
Kubica Adam
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How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
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