Results 61 to 70 of about 70,478 (262)

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

Multiple nodal solutions of the Kirchhoff-type problem with a cubic term

Advances in Nonlinear Analysis, 2022
In this article, we are interested in the following Kirchhoff-type problem (0.1)−a+b∫RN∣∇u∣2dxΔu+V(∣x∣)u=∣u∣2uinRN,u∈H1(RN),\left\{\begin{array}{l}-\left(a+b\mathop{\displaystyle \int }\limits_{{{\mathbb{R}}}^{N}}| \nabla u\hspace{-0.25em}{| }^{2}{\rm{d}}
Wang Tao, Yang Yanling, Guo Hui
doaj   +1 more source

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

Multiplicity of positive radial solutions of a quasilinear elliptic problem in a ball

Advances in Differential Equations, 2000
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
NJOKU F, OMARI, PIERPAOLO, ZANOLIN F.
openaire   +5 more sources

Morse index and uniqueness for positive solutions of radial $p$-Laplace equations [PDF]

Transactions of the American Mathematical Society, 2004
The authors consider positive radial solutions to a radial \(p\)-Laplace equation on the unit ball with Dirichlet boundary conditions. Using the spectrum of the linearized operator in a weighted space of radial functions, they derive the Morse index and use it to prove uniqueness and nondegeneracy in some particular cases.
A. Aftalion, PACELLA, Filomena
openaire   +3 more sources

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Three Solutions Theorem for p-Laplacian Problems with a Singular Weight and Its Application

Abstract and Applied Analysis, 2014
We prove Amann type three solutions theorem for one dimensional p-Laplacian problems with a singular weight function. To prove this theorem, we define a strong upper and lower solutions and compute the Leray-Schauder degree on a newly established ...
Yong-Hoon Lee, Seong-Uk Kim, Eun Kyoung Lee   +2 more
doaj   +1 more source

Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle, Andreas Leha, Volker Limmroth, Wolfram Windisch, Maximilian Zimmermann   +4 more
wiley   +1 more source

Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino, Lavanya Muthukumar, Evan L. Reynolds, Peter Todd, Sinem Ovunc, Sheng Chih Jin, Zitian Tang, Simone Thomas, PNRR Study Group, Ahmet Höke, Brian C. Callaghan, Sarah Berth, Vinay Chaudhry, David Cornblath, Leana Doherty, Lindsey Hayes, Hristelina Ilieva, Thomas Lloyd, Mohammad Khoshnoodi, Brett McCray, Brett Morrison, Bipasha Mukherjee‐Clavin, Lyle Ostrow, Michael Polydefkis, Ricardo Roda, Charlotte Sumner   +25 more
wiley   +1 more source

Lubrication Performance Analysis of RV Reducer Cycloid Tooth Profile Modification

Jixie chuandong, 2020
With the consideration of the thermal effect and piezo-viscous characteristic of lubricants， the numerical model of line contact elastohydrodynamic grease lubrication between cycloid gear and pin wheel is established， and the fully numerical solution of ...
Jun Wang, Zhilong Chen, Qunchao Chen, Wentao Li, Quan Wang, Daxing Zhao   +5 more
doaj