Results 51 to 60 of about 8,991,569 (289)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Existence of positive radial solution for the elliptic system on an exterior domain

Boundary Value Problems
This article discusses the existence of positive radial solution for the elliptic system { − △ u = K ( | x | ) f ( | x | , u , v , | ∇ u | ) , x ∈ Ω , − △ v = K ( | x | ) g ( | x | , u , v , | ∇ v | ) , x ∈ Ω , α 1 u + β 1 ∂ u ∂ n | ∂ Ω = 0 , α 2 v + β 2
Dan Wang, Yongxiang Li, Shengbin Yang
doaj   +1 more source

On existence and asymptotic behavior of solutions of elliptic equations with nearly critical exponent and singular coefficients

Electronic Journal of Qualitative Theory of Differential Equations, 2021
In this paper we study the existence and asymptotic behavior of solutions of $$-\Delta u=\mu\frac{u}{|x|^{2}}+|x|^{\alpha}u^{p(\alpha)-1-\varepsilon},\qquad u>0 \ \text{in}\ B_{R}(0)$$ with Dirichlet boundary condition.
Shiyu Li, Gongming Wei, Xueliang Duan
doaj   +1 more source

The radial positive solutions of the Matukuma equation in higher dimensional space: Singular solution

Journal of Differential Equations, 2012
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Wang, Biao, Zhang, Zheng-ce, Li, Yi
openaire   +2 more sources

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

A numerical study of radial basis function based methods for option pricing under one dimension jump-diffusion model [PDF]

The aim of this paper is to show how option prices in the Jump-diffusion model can be computed using meshless methods based on Radial Basis Function (RBF) interpolation.
Hubbert, Simon, Chan, Ron T.L.
core   +4 more sources

Localized radial solutions for a nonlinear p-Laplacian equation in $R^N$

Electronic Journal of Qualitative Theory of Differential Equations, 2008
We establish the existence of radial solutions to the p-Laplacian equation $ \Delta_p u + f(u)=0 $ in $\mathbb {R^N}$, where $f$ behaves like $|u|^{q-1}u$ when $u$ is large and $f(u) < 0$ for small positive $u$. We show that for each nonnegative integer
S. Pudipeddi
doaj   +1 more source

Radial symmetry and uniqueness for positive solutions of a Schrödinger type system

Mathematical and Computer Modelling, 2009
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Li Ma, Dezhong Chen
openaire   +3 more sources

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Radial solutions for a nonlocal boundary value problem

Boundary Value Problems, 2006
We consider the boundary value problem for the nonlinear Poisson equation with a nonlocal term −Δu=f(u,∫Ug(u)), u|∂U=0. We prove the existence of a positive radial solution when f grows linearly in u, using Krasnoselskiiés fixed ...
Luís Sanchez, Ricardo Enguiça   +1 more
doaj   +2 more sources