Results 61 to 70 of about 8,578,478 (315)

Nonexistence of positive radial solutions for a problem with singular potential

Advances in Nonlinear Analysis, 2014
This article completes the picture in the study of positive radial solutions in the function space 𝒟1,2(ℝN)∩L2(ℝN,|x|-αdx)∩Lp(ℝN)${{\mathcal {D}^{1,2}({\mathbb {R}^N}) \cap L^2({{\mathbb {R}^N}, | x |^{-\alpha } dx})\cap L^p({\mathbb {R}^N})}}$ for the ...
Catrina Florin
doaj   +1 more source

Positive solutions of nonlinear fourth-order boundary-value problems with local and non-local boundary conditions [PDF]

, 2008
We establish new existence results for multiple positive solutions of fourth-order nonlinear equations which model deflections of an elastic beam. We consider the widely studied boundary conditions corresponding to clamped and hinged ends and many non ...
J. R. L. Webb, Infante, G., Daniel Franco, Webb, J.R.L., Franco, D., Gennaro Infante   +5 more
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Radial Symmetry of Positive Solutions of Nonlinear Elliptic Equations

Journal of Differential Equations, 1999
Three results concerning the radial symmetry and asymptotic behaviour at \(x=\infty\) of positive solutions of \[ \Delta u = \varphi(\mid x\mid)u^{\lambda}, \quad x\in \mathbb{R}^n \] and \(|x|\) large are presented. Here \(\lambda>1\) and \(\varphi(r)\) is positive and continuous for \(r\) large. There are three cases which are separately analysed: (I)
openaire   +1 more source

Existence of Positive Radial Solutions of General Quasilinear Elliptic Systems [PDF]

, 2023
Let $\Omega\subset\mathbb R^{n}\ (n\geq2)$ be either an open ball $B_R$ centred at the origin or the whole space. We study the existence of positive, radial solutions of quasilinear elliptic systems of the form \begin{equation*} \left\{ \begin{aligned ...
Devine, Daniel
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Nonexistence of radial positive solutions for a nonpositone system in an annulus

Electronic Journal of Differential Equations, 2011
In this article we study the nonexistence of radial positive solutions for a nonpositone system in an annulus by using energy analysis and comparison methods.
Said Hakimi
doaj  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Bounded and large radially symmetric solutions for some (p,q)-Laplacian stationary systems

Electronic Journal of Differential Equations, 2012
This article concerns radially symmetric positive solutions of second-order quasilinear elliptic systems. In terms of the growth of the variable potential functions, we establish conditions such that the solutions are either bounded or blow up at ...
Adel Ben Dkhil, Noureddine Zeddini
doaj