Results 101 to 110 of about 5,230,574 (296)

Extreme Adverse Selection, Competitive Pricing, and Market Breakdown [PDF]

open access: yes
Extreme adverse selection arises when private information has unbounded support, and market breakdown occurs when no trade is the only equilibrium outcome.
Georg Nöldeke, George J. Mailath
core  

Solutions to Yang-Mills equations [PDF]

open access: yes, 2010
This article gives explicit solutions to the Yang-Mills equations. The solutions have positive energy that can be made arbitrarily small by selection of a parameter showing that Yang-Mills field theories do not have a mass gap.Comment: minor corrections ...
Jormakka, Jorma
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Does Private Tutoring Payoff? [PDF]

open access: yes
We assess the causal effect of private tutoring on the probability of university placement in Turkey. We find that tutoring increases the probability of being placed in a university when non-random selection is ignored.
Gurun, Ayfer, Millimet, Daniel L.
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Positive and negative selective assortment

open access: yesJournal of Theoretical Biology
In populations subject to evolutionary processes, the assortment of players with different genes or strategies can have a large impact on players' payoffs and on the expected evolution of each strategy in the population. Here we consider assortment generated by a process of partner choice known as selective assortment.
Segismundo S. Izquierdo   +2 more
openaire   +4 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

The Analysis of Selection and Training Model in Efforts to Increase Employee Performance PT. Arzuro Hr Performance [PDF]

open access: yes, 2019
The study conducted at PT Arzuro Kinerja SDM aims to prove empirically the effect of selection and training on employee performance, both partially and simultaneously.
Dinantara, M. D. (Mohamad)
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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