Results 41 to 50 of about 1,809,050 (267)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Adaptive positive-sequence fault-component directional relay for the two-terminal weak feed AC system based on positive-sequence impedance reconstruction control

open access: yesInternational Journal of Electrical Power & Energy Systems
The flexible DC transmission system for renewable energy has become a key solution for the large-scale integration of renewable energy into the power grid.
Junjie Hou   +4 more
doaj   +1 more source

Positive-unlabelled learning of glycosylation sites in the human proteome

open access: yesBMC Bioinformatics, 2019
Background As an important type of post-translational modification (PTM), protein glycosylation plays a crucial role in protein stability and protein function.
Fuyi Li   +7 more
doaj   +1 more source

Fault Detection for Microgrid Feeders Using Features Based on Superimposed Positive-Sequence Power

open access: yesJournal of Modern Power Systems and Clean Energy, 2023
With the integration of distributed generation (DG) into a microgrid, fault detection has become a major task to accomplish. A scheme for microgrid feeder protection based on a newly proposed feature, $\Delta \pmb{RP}$, defined as the ratio of the sum of
Salauddin Ansari   +2 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Balanced Current Control Strategy for Current Source Rectifier Stage of Indirect Matrix Converter under Unbalanced Grid Voltage Conditions

open access: yesEnergies, 2016
This paper proposes a balanced current control strategy for the current source rectifier (CSR) stage of an indirect matrix converter (IMC) under unbalanced grid voltage conditions. If the three-phase grid connected to the voltage source inverter (VSI) of
Yeongsu Bak, June-Seok Lee, Kyo-Beum Lee
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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