Results 131 to 140 of about 17,909,648 (352)
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Electronic Journal of Differential Equations, 2011 In this article, we study the existence and multiplicity of positive solutions for a nonlinear second-order multi-point boundary-value problem at resonance in Banach spaces. The arguments are based upon a specially constructed equivalent equation and
Weihua Jiang, Bin Wang
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Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Monotone and convex positive solutions for fourth-order multi-point boundary value problems
Boundary Value Problems, 2011 The existence results of multiple monotone and convex positive solutions for some fourth-order multi-point boundary value problems are established. The nonlinearities in the problems studied depend on all order derivatives. The analysis relies on a fixed
Chunfang Shen, Liu Yang, Weiguo Zhang
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Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Electronic Journal of Differential Equations, 2011 In this article, we study the self-adjoint second-order boundary-value problem with integral boundary conditions, $$displaylines{ (p(t)x'(t))'+ f(t,x(t))=0,quad tin (0,1),cr p(0)x'(0)=p(1)x'(1),quad x(1)=int_0^1x(s)g(s)ds, }$$ which involves an ...
Aijun Yang, Bo Sun, Weigao Ge
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Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
An elliptic problem with arbitrarily small positive solutions
Electronic Journal of Differential Equations, 2000 We show that for each $lambda > 0$, the problem $-Delta_p u = lambda f(u)$ in $Omega$, $u = 0$ on $partial Omega$ has a sequence of positive solutions $(u_n)_n$ with $max_{Omega} u_n$ decreasing to zero.
Pierpaolo Omari, Fabio Zanolin
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