Results 51 to 60 of about 456,539 (203)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

POSITIVE SOLUTIONS OF A NONLINEAR INTEGRAL EQUATION FROM BIOMATHEMATICS

Demonstratio Mathematica, 1999
The aim of the paper is to investigate the existence of positive continuous solutions of the nonlinear integral equation \(x(t)= \int^t_{t-\tau} f(s,x(s))ds\), arising in infectious disease. Sufficient conditions are given ensuring the existence of positive periodic continuous solutions of this equation, provided that \(f\) is a continuous function ...
openaire   +2 more sources

Boltzmann equations for mixtures of Maxwell gases: exact solutions and power like tails

, 2006
We consider the Boltzmann equations for mixtures ofMaxwell gases. It is shown that in certain limiting case the equations admit self-similar solutions that can be constructed in explicit form.
A. Pulvirenti, A. V. Bobylev, A. V. Bobylev, A. V. Bobylev, A. V. Bobylev, A. V. Bobylev, A. V. Bobylev, A. V. Bobylev, A. V. Bobylev, E. Gabetta, I. M. Gamba, M. H. Ernst, M. Krook, W. Feller   +13 more
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

A Sum Operator Method for the Existence and Uniqueness of Positive Solutions to a System of Nonlinear Fractional Integral Equations

Abstract and Applied Analysis, 2013
This paper is concerned with the existence and uniqueness of positive solutions for a Volterra nonlinear fractional system of integral equations. Our analysis relies on a fixed point theorem of a sum operator.
Jing Wu, Tunhua Wu
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Positive solutions of a fourth-order differential equation with integral boundary conditions

Mathematica Bohemica, 2022
The paper is concerned with the fourth-order two-point boundary value problem \[\left\{\begin{array}{l} u''''(t)+f(t,u(t))=0,\,\,\,t\in (0,1),\\ u'(0)=u'(1)=u''(0)=0,\,\,\,u(0)=\alpha[u], \end{array}\right.\leqno(1)\] where \(\alpha[u]=\int_0^1u(t)\,dA(t)\) is the Riemann-Stieltjes integral, \(A:[0,1]\to\mathbb{R}_+\) is a nondecreasing function of ...
Seshadev Padhi, John R. Graef
openaire   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

On Positive solutions of integral equations with the weighted Bessel potentials

Communications on Pure & Applied Analysis, 2019
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Wang, Mingchun, Xu, Jiankai, Wu, Huoxiong   +2 more
openaire   +2 more sources