Results 71 to 80 of about 457,753 (313)
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Monotone Iterative Schemes for Positive Solutions of a Fractional
, 2021 Min Jiang, Rengang Huang
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Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Positive solutions of nonlinear integral equations arising in infectious diseases
Journal of Mathematical Analysis and Applications, 1988 The following nonlinear integral equation (1) \(x(t)=\int^{t}_{t- \tau}f(s,x(s))ds\) can be interpreted as a model for the spread of certain infectious diseases. This equation is examined in the heading under the assumptions that f(t,x) is nonnegative and continuous on the set \(R\times R_+\), is \(\omega\)-periodic in t and such that \(f(t,0)=0\) for \
Guo, Dajun, Lakshmikantham, V
openaire +2 more sources
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Solvability of nonlinear integral equations of product type
Electronic Journal of Differential Equations, 2018 This article concerns nonlinear functional integral equations of product type. The first two equations set on a the positive half-axis encompass different classes of nonlinear integral equations and may involve the product of finitely many integral ...
Bilal Boulfoul +2 more
doaj
Open Mathematics, 2018 In this paper, the existence of positive solutions for systems of semipositone singular fractional differential equations with a parameter and integral boundary conditions is investigated. By using fixed point theorem in cone, sufficient conditions which
Hao Xinan, Wang Huaqing
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Positive solutions of a boundary value problem with integral boundary conditions [PDF]
, 2011 We consider boundary-value problems studied in a recent paper. We show that some existing theory developed by Webb and Infante applies to this problem and we use the known theory to show how to find improved estimates on parameters μ*, λ so ...
Webb, J.
core
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source