Evaluation of preclinical antipsychotic models used to support first‐in‐human clinical trials
British Journal of Pharmacology, Volume 183, Issue 7, Page 1364-1389, April 2026.Abstract Schizophrenia is regarded as a complex and heterogeneous psychiatric disorder, characterised by diverse symptoms and comorbidities, which complicate both clinical management and drug development. Current pharmacological treatment, primarily based on dopamine D2 receptor antagonism or partial agonism, which has not markedly progressed since the
Thi Viet Ha Nguyen +2 more
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Poroelasticity derived from the microstructure for intrinsically incompressible constituents. [PDF]
Z Angew Math PhysPenta R +3 more
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Macroscopic Market Making Games
Mathematical Finance, Volume 36, Issue 2, Page 352-373, April 2026.ABSTRACT Building on the macroscopic market making framework as a control problem, this paper investigates its extension to stochastic games. In the context of price competition, each agent is benchmarked against the best quote offered by the others. We begin with the linear case.
Ivan Guo, Shijia Jin
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Soliton solutions with bifurcation, sensitivity, chaotic and stability analysis of the (2+1)-dimensional Zoomeron equation using generalized Riccati equation mapping method. [PDF]
Sci RepZainab A +5 more
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On the Mean‐Field Limit of Consensus‐Based Methods
Mathematical Methods in the Applied Sciences, Volume 49, Issue 5, Page 4214-4240, 30 March 2026.ABSTRACT Consensus‐based optimization (CBO) employs a swarm of particles evolving as a system of stochastic differential equations (SDEs). Recently, it has been adapted to yield a derivative free sampling method referred to as consensus‐based sampling (CBS). In this paper, we investigate the “mean‐field limit” of a class of consensus methods, including
Marvin Koß, Simon Weissmann, Jakob Zech
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Mathematical modelling of ion diffusion and state of charge prediction in sodium ion batteries with time series analysis. [PDF]
Sci RepS S, Srivastava N, Hristov J.
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Homogenization With Guaranteed Bounds via Primal‐Dual Physically Informed Neural Networks
International Journal for Numerical Methods in Engineering, Volume 127, Issue 6, 30 March 2026.ABSTRACT Physics‐informed neural networks (PINNs) have shown promise in solving partial differential equations (PDEs) relevant to multiscale modeling, but they often fail when applied to materials with discontinuous coefficients, such as media with piecewise constant properties. This paper introduces a dual formulation for the PINN framework to improve
Liya Gaynutdinova +3 more
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Analytical and numerical properties of an extended angiogenesis PDEs model. [PDF]
J Math BiolDe Luca P, Marcellino L.
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Decadal Stability of Multi‐Scale Core‐Mantle Boundary in Core‐Reflections of Repeating Earthquakes
Geophysical Research Letters, Volume 53, Issue 5, 16 March 2026.Abstract Temporal changes near the core‐mantle boundary (CMB) would trigger insights into ongoing thermal and chemical interactions between the Earth's core and mantle. Here, we search for multidecadal temporal changes in the CMB topography and heterogeneity using waveform similarity analysis of core‐reflected phases (PcP, ScP, and ScS) from global ...
Tianyu Cui +5 more
wiley +1 more source
Modelling the impact of temperature and bird migration on the spread of West Nile virus. [PDF]
One HealthDuve P, Sauer FG, Lühken R.
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