Results 51 to 60 of about 88,651 (261)

Robot-assisted radical prostatectomy in the treatment of patients with clinically high-risk localized and locally advanced prostate cancer: single surgeons functional and oncologic outcomes

BMC Urology, 2022
Background Optimal treatment approaches for high-risk localized and locally advanced prostate cancer remain controversial and there are currently no standard treatments.
Tae Young Shin, Yong Seong Lee
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Treatment of the positive surgical margin following radical prostatectomy

Chinese Medical Journal, 2008
With increased incidence of prostate cancer and an increased number of patients undergoing radical prostatectomy in China, it will be necessary to elaborate the diagnosis, clinical significance and treatment of patients whose tumors have positive surgical margins following radical prostatectomy.Positive surgical margin, prostate cancer and radical ...
openaire   +2 more sources

Factors affecting surgical margin positivity in robotic assisted radical prostatectomy

Archivio Italiano di Urologia e Andrologia, 2017
Objectives: After radical prostatectomy, surgical margin positivity is an important indicator of biochemical recurrence and progression. In our study we want to compare the surgical margin positivity rates for retropubic radical prostatectomy (RRP) and robotic assisted radical prostatectomy (RALP) and investigate the factors affecting surgical margin ...
Mustafa, Yuksel, Kaan, Karamık, Hakan, Anıl, Ekrem, Islamoglu, Mutlu, Ates, Murat, Savas   +5 more
openaire   +3 more sources

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Variably Protease‐Sensitive Prionopathy: Two New Cases With Motor Neuron‐Dementia Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We describe two patients with variably protease‐sensitive prionopathy (VPSPr) who developed progressive upper motor neuron symptoms, insomnia, behavioral and cognitive decline, compatible with primary lateral sclerosis associated with frontotemporal dementia (FTD).
María Elena Erro, María Victoria Zelaya, Hasier Eraña, Javier Sánchez Ruiz de Gordoa, Fermín García‐Amigot, Anika Simonovska‐Serra, María Cristina Caballero, Isidre Ferrer, Ellen Gelpi, Ivonne Jericó, Joaquín Castilla   +10 more
wiley   +1 more source

Analysis of risk factors for positive margins in robot-assisted laparoscopic radical prostatectomy with Retzius-sparing (RS-RARP)

World Journal of Surgical Oncology
Objective This study aims to analyze the risk factors for positive surgical margins following robot-assisted laparoscopic radical prostatectomy with Retzius-sparing (RS-RARP) to provide a basis for clinical preoperative evaluation and intraoperative ...
Hua Yang, Bo Wu, Xuchang Liu, Kaiyuan Jia, Junyuan Bing, Yangjie Gao, Pengliang Shen, Xiaoming Cao   +7 more
doaj   +1 more source

Tenosynovial Giant Cell Tumors of the Hand: Analysis of Risk Factors for Surgical Margin and Recurrence

Medicina
Background and Objective: Tenosynovial giant cell tumors (TGCTs) are benign but potentially aggressive soft-tissue tumors, most commonly affecting the hand and frequently associated with local recurrence despite surgical treatment.
Tolgahan Cengiz, Şafak Aydın Şimşek, Ercan Bayar, Furkan Erdoğan, Alparslan Yurtbay, Hüseyin Sina Coşkun, Ahmet Pişkin, Nevzat Dabak   +7 more
doaj   +1 more source

Effect of surgical margin on recurrence based on preoperative circulating tumor cell status in hepatocellular carcinoma

EBioMedicine, 2020
Background: High rates of recurrence after resection severely worsen hepatocellular carcinoma (HCC) prognosis. This study aims to explore whether circulating tumor cell (CTC) is helpful in determine the appropriate liver resection margins for HCC ...
Kai-Qian Zhou, Yun-Fan Sun, Jian-Wen Cheng, Min Du, Yuan Ji, Peng-Xiang Wang, Bo Hu, Wei Guo, Yang Gao, Yue Yin, Jun-Feng Huang, Jian Zhou, Jia Fan, Xin-Rong Yang   +13 more
doaj   +1 more source