Results 61 to 70 of about 3,124,060 (293)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Stop Turning a Blind Eye: Tobacco Smoking Among Egyptian Patients With Schizophrenia
Frontiers in Psychiatry, 2019 Background: Patients with schizophrenia have considerably higher rates of mortality than general population. Multiple factors may play a role in this.
Hussien Elkholy +5 more
doaj +1 more source
Positive Affect and Adjustment to Perceived Racism [PDF]
, 2008 This research provided the first empirical investigation of the role of positive affect in moderating the relationship between perceived racism and depressive symptoms.
Edwards, Lisa M., Ong, Anthony D.
core +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Perception of burden by caregivers of patients with schizophrenia in relation to symptom profile
Annals of Indian Psychiatry, 2019 Background: Schizophrenia begins early in life causing significant long-lasting impairments. The caregivers face physical, psychological, and economic difficulties in taking care of them.
Bharathi Gunjahalli, P M Chougule
doaj +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Positive versus negative schizophrenia and basic symptoms
Comprehensive Psychiatry, 1992 In a sample of 71 Research Diagnostic Criteria (RDC) schizophrenic patients, the relationship among the basic symptoms measured by the Frankfurt Complaint Questionnaire and Andreasen and Olsen's types of schizophrenia was studied. The results do not support an overlap between negative and basic symptoms; rather, basic symptoms appear to be more ...
V, Peralta, M J, Cuesta, J, de Leon
openaire +2 more sources
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Sex differences and symptom based gray and white matter densities in schizophrenia
Cortica, 2022 We investigated the association between densities in gray matter (GMD) and white matter (WMD) phenotypes and positive (PS) and negative (NS) symptoms in 40 schizophrenia patients (SZ).
Adham Mancini Marïë
doaj +1 more source
Aisha Bano - The Role of KCNQ (Kv7) Potassium Channels in Schizophrenia Deficits [PDF]
, 2013 For years, studies have been conducted to treat the positive and negative symptoms and cognitive deficits of schizophrenia; it has allowed to treat the positive symptoms through regulation of dopaminergic neurons and dopamine pathways; however, we still ...
Bano, Aisha
core +1 more source