Results 71 to 80 of about 7,931,227 (299)

A Randomized Crossover Trial Comparing Autotitrating and Continuous Positive Airway Pressure in Subjects With Symptoms of Aerophagia: Effects on Compliance and Subjective Symptoms [PDF]

, 2017
Study Objective: To assess the benefit and tolerance of auto-titrating positive airways pressure (APAP) versus continuous positive airways pressure (CPAP) in subjects who experience aerophagia.\ud \ud Design: Prospective, two-week, double-blinded ...
Kevin Hanssen, Shirlaw, Teresa, Brett Duce, Hanssen, Kevin, Craig Hukins, Duce, Brett, Hukins, Craig, Teresa Shirlaw   +7 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

The Conceptualization of the Positive Cognitive Triad and Associations with Depressive Symptoms in Adolescents

, 2020
The positive cognitive triad (positive cognitions about the self, world, and future) has been considered a protective factor against depressive symptoms.
Sawyer, Michael G., Sawyer, Michael G, Adelson, Jill L, Adelson, Jill L., Spence, Susan H., Pittard, Caroline M., Pössel, Patrick, Sheffield, Jeanie, Pittard, Caroline M, Spence, Susan H   +9 more
core   +1 more source

Depressive symptoms in cancer patients compared with people from the general population: the role of sociodemographic and medical factors [PDF]

, 2003
This study examined depressive symptoms in 475 patients with cancer and in a reference group of 255 individuals without cancer from the general population and the associations of those symptoms with sociodemographic and medical factors.
Schroevers, M.J., Schroevers, M.J.; id_orcid, Sanderman, R., Ranchor, A.V.   +3 more
core   +2 more sources

Olanzapine has better efficacy compared to risperidone for treatment of negative symptoms in schizophrenia

Indian Journal of Psychiatry, 2016
Objective: The safety and efficacy profile of risperidone and olanzapine were compared in a double-blind trial that used doses widely accepted in clinical practice.
P. N. Suresh Kumar, P. K. Anish, V. Rajmohan   +2 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Effects of bilateral repetitive transcranial magnetic stimulation on prospective memory in patients with schizophrenia: A double‐blind randomized controlled clinical trial

Neuropsychopharmacology Reports
Aims To investigate effects of repetitive transcranial magnetic stimulation (rTMS) on the prospective memory (PM) in patients with schizophrenia (SCZ).
Fen Xue, Xin‐Fu Wang, Fan‐Ni Kong, Tian‐Lu Yin, Yu‐Hong Wang, Li‐Da Shi, Xiao‐Wen Liu, Hui‐Jing Yu, Li‐Jun Liu, Ping Zhu, Xiao‐Xue Qi, Xue‐Jing Xu, Hong‐Pu Hu, Su‐Xia Li   +13 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Differential Effects of Psychotic Illness on Directed and Random Exploration

Computational Psychiatry, 2020
Schizophrenia is associated with a number of deficits in decision-making, but the scope, nature, and cause of these deficits are not completely understood.
James A. Waltz, Robert C. Wilson, Matthew A. Albrecht, Michael J. Frank, James M. Gold   +4 more
doaj   +1 more source