Results 31 to 40 of about 153,438 (339)
The positivication of coalgebraic logics
arXiv: Logic in Computer Science, 2017 14 ...
Dahlqvist, Fredrik, Kurz, Alexander
openaire +5 more sources
FEBS Letters, EarlyView.C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi +5 more
wiley +1 more source
FEBS Letters, EarlyView.Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source
FEBS Letters, EarlyView.Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley +1 more source
IMPLIKASI FILSAFAT POSITIVISME TERHADAP ILMU HUKUM DAN PENEGAKANNYA
Unes Journal of Swara Justisia, 2023 Positivism has developed and dominated the flow of legal thought to this day. This study aims to examine the implications of positivism for law and its enforcement.
Made Oka Cahyadi Wiguna
doaj +1 more source
A working model for cytoplasmic assembly of H/ACA snoRNPs
FEBS Letters, EarlyView.Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley +1 more source
Studia Historiae Scientiarum, 2017 This article addresses the appropriation of positivist thought by Ukrainian intellectuals in the second half of the nineteenth century, in particular in the field of philosophy of history.
Vyacheslav Artyukh
doaj +3 more sources
Why the epistemologies of trust researchers matter [PDF]
, 2015 In this thought piece we take stock of and evaluate the nature of knowledge production in the field of trust research by examining the epistemologies of 167 leading trust scholars, who responded to a short survey.
Bachmann, Reinhard +3 more
core +3 more sources
FEBS Letters, EarlyView.Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
Ontology and Reason Giving in Law [PDF]
, 2016 John Gardner has noted that legal positivism is more a theory of legal validity than it is a theory about law ’ s nature. 1 This is true in that one can be a legal positivist and hold a variety of different theories about law ’ s nature, but not to the
Ehrenberg, Kenneth M.
core +1 more source