Results 51 to 60 of about 153,438 (339)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Espaço Jurídico, 2015 On the basis of the distinction between two forms of positivism and three forms of non-positivism, I argue that only one of these five concepts of law is defensible: inclusive non-positivism. The basis of my argument is the correctness thesis, which says
Robert Alexy
doaj +1 more source
Bases biológicas de la ética de Popper:entre el iusnaturalismo y el positivismo [PDF]
, 2005 The biological bases of Popper¿s Ethics are expounded in this article. But these biological bases do not place Popper¿s thought in the sphere of iusnaturalism, because normative laws are made and can be changed by men.
Muñoz Ferriol, Amparo
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Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
FEBS Letters, EarlyView.This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source
Fighting a Resurgent Hyper-Positivism in Education is Music to My Ears
, 2015 In this article, I argue that one of the gifts of the Age of Enlightenment, the ability to measure, to experiment, to predict—turned rancid by hyper-positivism—is re-asserting itself globally in the field of education (including music education). I see a
Williams, Hakim Mohandas Amani
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FEBS Letters, EarlyView.Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source
Positivism versus self-determination: the contradictions of Soviet international law [PDF]
, 2008 Against expectations that the turn away from state socialism would likewise initiate a turn away from Marxist thought, recent years have seen a resurgence of interest in Marxism and its reassessment by a new generation of theorists.
Bowring, Bill
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Positivism and Conventionalism [PDF]
Canadian Journal of Law & Jurisprudence, 1999 All positivists hold that law has social foundations. According to H.L.A. Hart, for example, the legal system rests on customary social norms followed by judges and other officials: norms that recognize other norms as belonging to the system and norms that provide for the application and alteration of the system’s primary norms.
openaire +2 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Normativity of law and interpretive approaches : (a discussion on the relation between law and reason) [PDF]
, 2012 The debates about the interrelations between reason and law have undergone a change after the eighteenth century. References to the recta ratio of jusnaturalistic tradition have not disappeared, but other comprehensions of legal reason have developed ...
Batalha, Carlos Eduardo
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