Results 61 to 70 of about 18,081 (306)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Approaching Standardization of Bovine Ovarian Cortex Cryopreservation: Impact of Cryopreservation Protocols and Tissue Size on Preantral Follicle Population

open access: yesAnimals
Cryopreservation of bovine ovarian cortical tissue offers a promising strategy for preserving female fertility and genetic resources, yet outcomes remain variable and influenced by both protocol and tissue size.
Paula Romero   +6 more
doaj   +1 more source

Induction of CD44 variant 9-expressing cancer stem cells might attenuate the efficacy of chemoradioselection and Worsens the prognosis of patients with advanced head and neck cancer. [PDF]

open access: yesPLoS ONE, 2015
At our institute, a chemoradioselection strategy has been used to select patients for organ preservation on the basis of response to an initial 30-40 Gy concurrent chemoradiotherapy (CCRT).
Takeichiro Aso   +10 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Symmetry Classification of Many-Body Lindbladians: Tenfold Way and Beyond

open access: yesPhysical Review X, 2023
We perform a systematic symmetry classification of many-body Lindblad superoperators describing general (interacting) open quantum systems coupled to a Markovian environment.
Lucas Sá, Pedro Ribeiro, Tomaž Prosen
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Semi-Rings, Semi-Vector Spaces, and Fractal Interpolation

open access: yesFractal and Fractional
In this paper, we introduce fractal interpolation on complete semi-vector spaces. This approach is motivated by the requirements of the preservation of positivity or monotonicity of functions for some models in approximation and interpolation theory. The
Peter Massopust
doaj   +1 more source

$L^p$ positivity preservation and self-adjointness on incomplete Riemannian manifolds

open access: yes, 2023
The aim of this paper is to prove a qualitative property, namely the preservation of positivity, for Schr\"odinger-type operators acting on $L^p$ functions defined on (possibly incomplete) Riemannian manifolds.
Bisterzo, Andrea, Veronelli, Giona
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The $L^{\infty }$-positivity Preserving Property and Stochastic Completeness

open access: yesPotential Analysis, 2022
We say that a Riemannian manifold satisfies the $L^p$-positivity preserving property if $(-Δ+ 1)u\ge 0$ in a distributional sense implies $u \ge 0$ for all $ u \in L^p$.While geodesic completeness of the manifold at hand ensures the $L^p$-positivity preserving property for all $p \in (1, +\infty)$, when $p = + \infty$ some assumptions are needed.
Bisterzo, A, Marini, L
openaire   +3 more sources

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