Results 141 to 150 of about 15,388 (303)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Comparative study of high-order positivity-preserving WENO schemes

, 2012
In gas dynamics and magnetohydrodynamics flows, physically, the density ρ and the pressure p should both be positive. In a standard conservative numerical scheme, however, the computed internal energy is obtained by subtracting the kinetic energy from ...
Kotov, D. V., Yee, Helen C., Sjögreen, Bjorn   +2 more
core  

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

A Computational Modeling for Semi-Coupled Multiphase Flow in Atmospheric Icing Conditions

Journal of Aerospace Technology and Management, 2015
A two-dimensional second-order positivity-preserving finite volume upwind scheme is developed for a semi-coupled algorithm involving the air and droplet flow fields in the Eulerian frame in which shares the grid for each phase.
SungKi Jung
doaj  

On positivity preservers with constant coefficients and their generators

Journal of Algebra
In this work we study positivity preservers $T:\mathbb{R}[x_1,\dots,x_n]\to\mathbb{R}[x_1,\dots,x_n]$ with constant coefficients and define their generators $A$ if they exist, i.e., $\exp(A) = T$. We use the theory of regular Fréchet Lie groups to show the first main result.
openaire   +2 more sources

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Recovering Complete Positivity of Non-Markovian Quantum Dynamics with Choi-Proximity Regularization

Physical Review X
A relevant problem in the theory of open quantum systems is the lack of complete positivity of dynamical maps obtained after weak-coupling approximations, a famous example being the Redfield master equation.
Antonio D’Abbruzzo, Donato Farina, Vittorio Giovannetti   +2 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

A dynamically consistent and time-efficient numerical design for the reaction diffusion model in three space dimensions

Applied Mathematics in Science and Engineering
In this study, a famous Brusselator non-linear model arising in enzymatic and triple collision is considered to analyse its various physical features. These features include positivity, stability, and convergence.
Nauman Ahmed, Muhammad Rafiq, Muhammad Aziz-ur Rehman, Tahira Sumbal Shaikh, Aisha M. Alqahtani, Ilyas Khan, Muhammad Imran, Shafiullah Niazai   +7 more
doaj   +1 more source