Results 71 to 80 of about 15,388 (303)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
, 2013 This paper proposes the sufficient conditions for positivity preserving cubic boundary curves defined on rectangular grid using polynomial solution of fourth order linear PDEs in order to improve the positivity preserving of the interpolating surface. We
Ahmed Kherd +5 more
core +1 more source
A Positivity-Preserving Numerical Scheme for Nonlinear Option Pricing Models
Journal of Applied Mathematics, 2012 A positivity-preserving numerical method for nonlinear Black-Scholes models is developed in this paper. The numerical method is based on a nonstandard approximation of the second partial derivative.
Shengwu Zhou, Wei Li, Yu Wei, Cui Wen
doaj +1 more source
Frontiers in Physics, 2020 This study is concerned with finding a numerical solution to the delay epidemic model with diffusion. This is not a simple task as variables involved in the model exhibit some important physical features. We have therefore designed an efficient numerical
Muhammad Jawaz +7 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Positivity-preserving scheme for two-dimensional advection-diffusion equations including mixed derivatives [PDF]
, 2018 In this work, we propose a positivity-preserving scheme for solving two-dimensional advection-diffusion equations including mixed derivative terms, in order to improve the accuracy of lower-order methods.
Vann, Roderick G L +5 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Markov Processes Associated With Positivity Preserving Coercive Forms
, 1995 Ma Z-M, Röckner M. Markov Processes Associated With Positivity Preserving Coercive Forms. Canadian Journal of Mathematics = Journal Canadien de Mathématiques .
Zhi-Ming Ma +3 more
core +1 more source
On positive approximations of positive diffusions
Lietuvos Matematikos Rinkinys, 2007 For positive diffusions, we construct split-step second-order weak approximations preserving the positivity property. For illustration, we apply the construction to some popular stochastic differential equations such as Verhulst, CIR, and CKLS equations.
Vigirdas Mackevičius
doaj +1 more source