Results 181 to 190 of about 1,853,552 (305)

Nucleus basalis functional connectivity aberrations in temporal lobe epilepsy and improvements after successful epilepsy surgery

open access: yesEpilepsia, EarlyView.
Abstract Objective Resective surgery achieves seizure freedom in approximately 60%–80% of patients with drug‐resistant temporal lobe epilepsy (TLE), yet the extent to which seizure cessation permits recovery of disrupted functional brain networks remains unclear.
Addison C. Cavender   +15 more
wiley   +1 more source

Ophelia Syndrome: Acute Stupor as a Primary Manifestation of Hodgkin Lymphoma Diagnosed by Fluorodeoxyglucose Positron Emission Tomography. [PDF]

open access: yesCureus
Cortes Bravo A   +5 more
europepmc   +1 more source

Frequent cannabis use and the association with seizure burden in drug‐resistant epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Cannabis use has increased substantially, with modern products characterized by high tetrahydrocannabinol concentrations and variable composition. The relationship between frequent cannabis use and epilepsy outcomes remains uncertain. We examined the association between frequent cannabis use and epilepsy severity, clinical phenotype,
Santiago Philibert‐Rosas   +16 more
wiley   +1 more source

How should etiology change the classification of the epilepsies? Report from the ILAE 2021–2025 Terminology Commission

open access: yesEpilepsia, EarlyView.
Abstract The classification of the epilepsies has traditionally relied on clinical and electroencephalographic features. However, advancements in molecular genetics, neuroimaging, and our understanding of epilepsy pathophysiology necessitate a shift toward an etiology‐based approach.
Nicola Specchio   +15 more
wiley   +1 more source

Prognostic value of left ventricular hypertrophy assessed with <sup>15</sup>O-water positron emission tomography. [PDF]

open access: yesEur Heart J Imaging Methods Pract
Sigfridsson J   +6 more
europepmc   +1 more source

Multimodal modeling of the ictal onset zone in refractory insular epilepsy and seizure outcome of magnetic resonance‐guided laser interstitial therapy: A pediatric single‐center retrospective study

open access: yesEpilepsia, EarlyView.
Abstract Objective This study was undertaken to evaluate seizure outcomes after magnetic resonance‐guided laser interstitial thermal therapy (MRgLITT) in children with insular epilepsy and to assess how the extent of ablation overlaps with multimodal definitions of the ictal onset zone (IOZ).
Lelio Guida   +15 more
wiley   +1 more source

Selective γ8 transmembrane α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor regulatory protein negative allosteric modulators: Efficacy in preclinical antiseizure models

open access: yesEpilepsia, EarlyView.
Abstract Objective RAP‐219, a potent selective negative allosteric modulator (NAM) of α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor (AMPAR) associated with γ8 transmembrane AMPAR regulatory protein (TARPγ8), is in phase 3 development for refractory focal epilepsy. This study was undertaken to assess efficacy and motor function following
Jose A. Matta   +5 more
wiley   +1 more source

Reasons for not reoperating and outcomes of reoperation after seizure recurrence in pediatric epilepsy surgery: A population‐based study

open access: yesEpilepsia, EarlyView.
Abstract Objective Epilepsy surgery is an established and effective treatment for children with drug‐resistant epilepsy. Although the majority of patients become seizure‐free postoperatively, 20%–40% experience seizure recurrence. Although repeat surgery can achieve seizure freedom in selected cases, the reasons children with seizure recurrence do not ...
Vincent Zheng   +5 more
wiley   +1 more source

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