Results 61 to 70 of about 456,556 (361)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

[11C]-L-Methionine positron emission tomography in the management of children and young adults with brain tumors

, 2009
Only a few Methyl-[11C]-l-methionine (MET) positron emission tomography (PET) studies have focused on children and young adults with brain neoplasm. Due to radiation exposure, long scan acquisition time, and the need for sedation in young children MET ...
Johannes C. Klein, Frank Berthold, Kracht, L., Heiss, Wolf-Dieter, Herholz, Karl; id_orcid, Galldiks, N., Herholz, Karl, Klein, Johannes C., Heiss, Wolf Dieter, Jacobs, Andreas H., Hrvoje Miletic, Heiss, W., Lutz W. Kracht, Wolf-Dieter Heiss, Berthold, Frank, Klein, Johannes Christian, Jacobs, A., Kracht, Lutz W., Karl Herholz, Galldiks, Norbert, Miletic, Hrvoje, Herholz, K., Berthold, F., Norbert Galldiks, Klein, J., Kracht, Lutz Walter, Andreas H. Jacobs, Miletic, H.   +27 more
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source

Cortical Activity During an Attack of Ménière's Disease—A Case Report

Frontiers in Neurology, 2021
Background: Ménière's disease (MD) is a chronic peripheral vestibular disorder with recurrent episodes of vertigo accompanied by fluctuating hearing loss, tinnitus and aural fullness in the affected ear. There are several unanswered fundamental questions
Louise Devantier, Louise Devantier, Allan K. Hansen, Jens-Jacob Mølby-Henriksen, Michael Pedersen, Michael Pedersen, Per Borghammer, Therese Ovesen, Therese Ovesen, Måns Magnusson   +9 more
doaj   +1 more source

Detectability of colorectal neoplasia with fluorine-18-2-fluoro-2-deoxy-D-glucose positron emission tomography and computed tomography (FDG-PET/CT)

, 2011
The purpose of this study was to analyze the detectability of colorectal neoplasia with fluorine-18-2-fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography (FDG-PET/CT). Data for a total of 492 patients who had undergone both PET/CT
Saito, Shunsuke, Sakiko Hiraoka, Tomoko Hirakawa, Kato, Jun, Shunsuke Saito, Hirakawa, Tomoko, Kaji, Eisuke, Higashi, Reiji, Sakuma Takahashi, Mitsuhiro Akita, Hori, Keisuke, Yoshihiro Okumura, Toshio Uraoka, Akita, Mitsuhiro, Kazuhide Yamamoto, Okumura, Yoshihiro, Hiraoka, Sakiko, Jun Kato, Reiji Higashi, Takahashi, Sakuma, Yamamoto, Kazuhide, Eisuke Kaji, Uraoka, Toshio, Keisuke Hori, Suzuki, Hideyuki, Hideyuki Suzuki   +25 more
core   +1 more source

Development of Novel Fluorine-18 Labeled PET Radioligands for Monoamine Oxidase B (MAO-B) [PDF]

, 2013
Monoamine oxidases (MAO-A and MAO-B) are important enzymes regulating the levels of monoaminergic neurotransmitters. Selective and irreversible MAO-B inhibitors such as L-deprenyl and rasagiline are clinically used for the treatment of psychiatric and ...
Nag, Sangram
core   +1 more source

89Zr-Immuno-Positron Emission Tomography in Oncology: State-of-the-Art 89Zr Radiochemistry

Bioconjugate chemistry, 2017
Immuno-positron emission tomography (immunoPET) with 89Zr-labeled antibodies has shown great potential in cancer imaging. It can provide important information about the pharmacokinetics and tumor-targeting properties of monoclonal antibodies and may help
S. Heskamp, R. Raavé, O. Boerman, M. Rijpkema, Victor Goncalves, F. Denat   +5 more
semanticscholar   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Multisite Experience of the Safety, Detection Rate and Diagnostic Performance of Fluciclovine (18F) Positron Emission Tomography/Computerized Tomography Imaging in the Staging of Biochemically Recurrent Prostate Cancer

Journal of Urology, 2017
Purpose: Sensitive detection of cancer foci in men experiencing biochemical recurrence following initial treatment of prostate cancer is of great clinical significance with a possible impact on subsequent treatment choice.
T. Bach‐Gansmo, C. Nanni, P. Nieh, L. Zanoni, T. Bogsrud, Heidi Sletten, Katrine Korsan, J. Kieboom, Funmilayo Tade, Oluwaseun A. Odewole, A. Chau, P. Ward, M. Goodman, S. Fanti, D. Schuster, Frode Willoch   +15 more
semanticscholar   +1 more source