Results 51 to 60 of about 456,556 (361)

PET Imaging of Neuroinflammation in Alzheimer’s Disease

Frontiers in Immunology, 2021
Neuroinflammation play an important role in Alzheimer’s disease pathogenesis. Advances in molecular imaging using positron emission tomography have provided insights into the time course of neuroinflammation and its relation with Alzheimer’s disease ...
Rong Zhou, Bin Ji, Yanyan Kong, Limei Qin, Wuwei Ren, Yihui Guan, Ruiqing Ni, Ruiqing Ni   +7 more
doaj   +1 more source

Positron emission tomography compartmental models: A basis pursuit strategy for kinetic modelling

, 2002
A kinetic modelling approach for the quantification of in vivo tracer studies with dynamic positron emission tomography (PET) is presented. The approach is based on a general compartmental description of the tracer’s fate in vivo and determines a ...
Roger N. Gunn, Gunn, S R, Turkheimer, F E ; id_orcid, Aston, J A D, John A. D. Aston, Cunningham, T J, Turkheimer, F.E., Aston, J.A.D., Gunn, S.R., Gunn, R.N., Federico E. Turkheimer, Steve R. Gunn, Vincent J. Cunningham, Cunningham, V.J., Gunn, R N   +14 more
core   +1 more source

Development and application of dedicated positron emission tomography (PET) systems in prostate cancer diagnostics

Journal of Education, Health and Sport, 2017
Introduction: One of the most important parameter in prostate cancer diagnostics is fast and accurate diagnosis. The important role plays finding cancer markers in blood but also advanced medical imaging systems technology, that allows for faster and ...
Mateusz Wędrowski, Marta Maruszak, Ewelina Wędrowska, Elżbieta Piskorska, Bogdan Małkowski   +4 more
doaj   +3 more sources

Estimation of activity of administered 18F-fluorodeoxyglucose by measurement of the dose equivalent rate on the right temporal region of the head

EJNMMI Physics, 2016
Background Positron emission tomography (PET) with 18F-fluorodeoxyglucose (FDG) is now a routine procedure for the management of cancer patients. Intravenous administration of FDG is sometimes halted due to troubles. In such cases, estimations of the FDG
Kenta Sakaguchi, Makoto Hosono, Tomomi Imamura, Naomi Takahara, Misa Hayashi, Yuko Yakushiji, Kazunari Ishii, Tatsuro Uto, Takamichi Murakami   +8 more
doaj   +1 more source

Fragile X Mental Retardation Protein and Cerebral Expression of Metabotropic Glutamate Receptor Subtype 5 in Men with Fragile X Syndrome: A Pilot Study

Brain Sciences, 2022
Multiple lines of evidence suggest that a deficiency of Fragile X Mental Retardation Protein (FMRP) mediates dysfunction of the metabotropic glutamate receptor subtype 5 (mGluR5) in the pathogenesis of fragile X syndrome (FXS), the most commonly known ...
James Robert Brašić, Jack Alexander Goodman, Ayon Nandi, David S. Russell, Danna Jennings, Olivier Barret, Samuel D. Martin, Keith Slifer, Thomas Sedlak, Anil Kumar Mathur, John P. Seibyl, Elizabeth M. Berry-Kravis, Dean F. Wong, Dejan B. Budimirovic   +13 more
doaj   +1 more source

Association between cognitive performance and cortical glucose metabolism in patients with mild Alzheimer's disease [PDF]

, 2005
Background: Neuronal and synaptic function in Alzheimer's disease (AD) is measured in vivo by glucose metabolism using positron emission tomography (PET). Objective: We hypothesized that neuronal activation as measured by PET is a more sensitive index of
Teipel, S. J., Schwaiger, Markus, Drzezga, A., Hampel, H., Bokde, ALW, Leinsinger, G., Born, C., Thissen, J., Bartenstein, P., Dong, W., Schwaiger, M., Möller, Hans-Jürgen   +11 more
core   +1 more source

Innovations in instrumentation for positron emission tomography

Seminars in nuclear medicine, 2018
Positron emission tomography (PET) scanners are sophisticated and highly sensitive biomedical imaging devices that can produce highly quantitative images showing the three-dimensional distribution of radiotracers inside the body.
E. Berg, S. Cherry
semanticscholar   +1 more source

Development of an automated method for in-house production of sodium 18F-fluoride for injection: process validation as a step toward routine clinical application

EJNMMI Radiopharmacy and Chemistry
Background Sodium 18F-fluoride for injection can be easily cyclotron-produced and purified, as a simple inorganic salt, by adsorption/desorption onto an anion-exchange cartridge and then dispensed for clinical use.
Marija Atanasova Lazareva, Maja Chochevska, Katerina Kolevska, Maja Velickovska, Filip Jolevski, Paulina Apostolova, Ana Ugrinska, Emilija Janevik-Ivanovska   +7 more
doaj   +1 more source

The Application of PET/CT in Predicting and Evaluating the Therapeutic Response in Chemotherapy of Solid Tumor

Journal of Isotopes, 2017
Three aspects of the application of PET/CT in solid tumor chemotherapy were summarized, including the selection of evaluation criteria, the proper time of using PET/CT in the evaluation and the parameters of PET/CT in evaluating the response of ...
positron emission tomography solid tumor chemotherapy predicton of therapeutic response
doaj   +1 more source

Tau positron emission tomography imaging in tauopathies: The added hurdle of off-target binding

Alzheimer's & Dementia, 2018
Ligands targeting tau for use with positron emission tomography have rapidly been developed during the past several years, enabling the in vivo study of tau pathology in patients with Alzheimer's disease and related non‐Alzheimer's disease tauopathies ...
Laetitia Lemoine, A. Leuzy, K. Chiotis, E. Rodriguez-Vieitez, A. Nordberg   +4 more
semanticscholar   +1 more source