Results 81 to 90 of about 366,454 (332)

Advances in Halide Perovskites for Photon Radiation Detectors

Advanced Materials Technologies, EarlyView.
This work highlights recent progress in perovskite‐based photon radiation detectors, covering organic–inorganic hybrid, inorganic, lead‐free double, and vacancy‐ordered halide perovskites. Their detection performance is compared, material‐specific advantages and challenges are examined, and provides insight into current limitations and future ...
Liangling Wang, Jieqi Wang, Xiaojun Cui, Carsten Ronning   +3 more
wiley   +1 more source

Innovations in Instrumentation for Positron Emission Tomography.

Seminars in nuclear medicine, 2018
PET scanners are sophisticated and highly sensitive biomedical imaging devices that can produce highly quantitative images showing the 3-dimensional distribution of radiotracers inside the body.
E. Berg, S. Cherry
semanticscholar   +1 more source

CMOS‐Compatible Short‐Wave Infrared Linear Arrays of Ge‐on‐Si Avalanche Photodiodes

Advanced Photonics Research, EarlyView.
The fabrication and characterization of a new type of surface‐illuminated Si‐based avalanche photodiode array operating in the short‐wave infrared region using germanium as the absorber and silicon as the multiplier is reported. The demonstration of an avalanche gain of 24 at a temperature of 378 K allows the devices to operate in outdoor environments.
Mrudul Modak, Muhammad M. A. Mirza, Xin Yi, Qingyu Tian, Lisa Saalbach, Fiona Fleming, Jaroslaw Kirdoda, Derek C. S. Dumas, Xiao Jin, Charlie Smith, Levi Tegg, Sima Aminorroaya Yamini, John P. R. David, Douglas J. Paul, Ross W. Millar, Gerald S. Buller   +15 more
wiley   +1 more source

Identifying active vascular microcalcification by 18F-sodium fluoride positron emission tomography

Nature Communications, 2015
Vascular calcification is a complex biological process that is a hallmark of atherosclerosis. While macrocalcification confers plaque stability, microcalcification is a key feature of high-risk atheroma and is associated with increased morbidity and ...
Agnese Irkle, A. Vesey, David Y. Lewis, J. Skepper, Joseph L. E. Bird, M. Dweck, Francis R. Joshi, Ferdia A Gallagher, Elizabeth A. Warburton, Martin R. Bennett, Kevin M. Brindle, D. E. Newby, J. Rudd, Anthony P. Davenport   +13 more
semanticscholar   +1 more source

A SERS‐Based Antibody‐Aptamer Sandwich Assay for Extracellular Vesicle‐Associated Tau Detection Using Gold Nanoparticles

Advanced Sensor Research, EarlyView.
Tau protein plays a critical role in the pathology of Alzheimer's disease, utilizing extracellular vesicles (EVs) as a mechanism for intercellular transmission. This study develops a highly sensitive sandwich assay biosensor for detecting and quantifying tau‐associated EVs using surface‐enhanced Raman spectroscopy (SERS).
Saqer Al Abdullah, Samaneh Ghadami, Md. Arifur Rahman Khan, Farbod Ebrahimi, Kyle Nowlin, Tetyana Ignatova, Kristen Dellinger   +6 more
wiley   +1 more source

BAG2 Inhibits Cervical Cancer Progression by Modulating Type I Interferon Signaling through Stabilizing STING

Advanced Science, EarlyView.
Based on IP‐MS analysis, BAG2 is confirmed to be essential for ubiquitination and protein homeostasis regulation of STING in cervical cancer. BAG2 inhibits the ubiquitination and degradation of STING by forming a complex with STUB1, thereby activating the type I IFN signaling pathway and inhibiting the development of cervical cancer.
Shijie Yao, Siming Chen, Anjin Wang, Ziyan Liang, Xuelian Liu, Yang Gao, Hongbing Cai   +6 more
wiley   +1 more source

Existing Pittsburgh Compound-B positron emission tomography thresholds are too high: statistical and pathological evaluation.

Brain : a journal of neurology, 2015
Amyloid-β, a hallmark of Alzheimer's disease, begins accumulating up to two decades before the onset of dementia, and can be detected in vivo applying amyloid-β positron emission tomography tracers such as carbon-11-labelled Pittsburgh compound-B.
S. Villeneuve, G. Rabinovici, Brendan I. Cohn-Sheehy, Cindee M. Madison, Nagehan Ayakta, P. Ghosh, R. La Joie, S. K. Arthur-Bentil, J. Vogel, Shawn M. Marks, M. Lehmann, H. Rosen, B. Reed, J. Olichney, A. Boxer, B. Miller, E. Borys, Lee‐way Jin, E. Huang, L. Grinberg, C. DeCarli, W. Seeley, W. Jagust   +22 more
semanticscholar   +1 more source

Noninvasive Assessment of β‐Secretase Activity Through Click Chemistry‐Mediated Enrichment of Neuronal Extracellular Vesicles to Detect Alzheimer's Disease

Advanced Science, EarlyView.
This study presents the NEV β‐secretase activity assay, a groundbreaking method for noninvasive evaluation of β‐secretase activity in Alzheimer's disease (AD) patients, enabling the generation of individualized β‐secretase activity profiles.
Hyoyong Kim, Junseok Lee, Audrey Qian, You‐Ren Ji, Ryan Zhang, Qixin Hu, Christopher Kazu Williams, Han‐Yu Chuang, Matthew D. Smalley, Yaya Xu, Liang Gao, Mary C. Mayo, Ting Zhang, Edwin M. Posadas, Zaldy S. Tan, Harry V. Vinters, Keith Vossel, Shino Magaki, Yazhen Zhu, Hsian‐Rong Tseng   +19 more
wiley   +1 more source

Clinically Valuable Quality Control for PET/MRI Systems: Consensus Recommendation From the HYBRID Consortium

Frontiers in Physics, 2019
Quality control (QC) of medical imaging devices is essential to ensure their proper function and to gain accurate and quantitative results. Therefore, several international bodies have published QC guidelines and recommendations for a wide range of ...
Alejandra Valladares, Sahar Ahangari, Thomas Beyer, Ronald Boellaard, Ronald Boellaard, Zacharias Chalampalakis, Claude Comtat, Laura DalToso, Adam E. Hansen, Michel Koole, Jane Mackewn, Paul Marsden, Johan Nuyts, Francesco Padormo, Ronald Peeters, Sebastian Poth, Esteban Solari, Ivo Rausch   +17 more
doaj   +1 more source

The State of High‐Resolution Imaging of the Human Inner Ear: A Look Into the Black Box

Advanced Science, EarlyView.
High‐resolution imaging of the cochlea is challenged by numerous unique aspects of this organ, where sensorineural cells, crucial for hearing, are too small for conventional modalities like magnetic resonance imaging and computed tomography. This article reviews current imaging techniques, emerging technologies, and innovations aimed at improving ...
Shelley Batts, Nancy Pham, Guillermo Tearney, Konstantina M. Stankovic   +3 more
wiley   +1 more source