Results 131 to 140 of about 557,117 (392)

Fluorinated Carnitine Derivatives as Tools to Visualise Carnitine Transport and Metabolism

Advanced Science, EarlyView.
Fluorinated carnitines, fluoromethyl carnitine (FMC) and [18F]fluoromethyl carnitine ([18F]FMC), are synthesised and established as powerful probes to interrogate carnitine biology. The multimodal detection facilitated by fluorine labelling, including 19F NMR, mass spectrometry, and positron emission tomography imaging, allowed for visualisation of ...
Richard S. Edwards, Ella‐May Hards, Sofia N. dos Santos, Hannah E. Greenwood, Madeleine E. George, Andrea Emanuelli, Muhammet Tanc, Thomas R. Eykyn, Timothy H. Witney   +8 more
wiley   +1 more source

Morphological and functional alterations in type 2 diabetes pancreata assessed with MRI-based metrics and [18F]FP-(+)-DTBZ PET

Frontiers in Endocrinology
ObjectiveTo determine if combining PET-derived beta-cell mass (BCM) estimates with MRI-based morphology metrics improves the prediction of beta-cell functional mass in type 2 diabetes (T2D).MethodsWe performed a retrospective analysis of 40 participants ...
Seyed Faraz Nejati, Faranak Ebrahimian Sadabad, Rui Ren, Yuan Huang, Jason Bini   +4 more
doaj   +1 more source

Prognostic value of subventricular zone involvement in relation to tumor volumes defined by fused MRI and O-(2-[18F]fluoroethyl)-L-tyrosine (FET) PET imaging in glioblastoma multiforme

Radiation Oncology, 2019
Background Subventricular zone (SVZ) involvement is associated with a dismal prognosis in patients with glioblastoma multiforme (GBM). Dual-time point (dtp) O-(2-[18F]fluoroethyl)-L-tyrosine (FET) PET/CT (PET) may be a time- and cost-effective ...
Maciej Harat, Bogdan Małkowski, Krzysztof Roszkowski   +2 more
doaj   +1 more source

Selective and divided attention during visual discriminations of shape, color, and speed: functional anatomy by positron emission tomography

Journal of Neuroscience, 1991
Positron emission tomography (PET) was used to identify the neural systems involved in discriminating the shape, color, and speed of a visual stimulus under conditions of selective and divided attention.
M. Corbetta, F. Miezin, S. Dobmeyer, G. Shulman, S. Petersen   +4 more
semanticscholar   +1 more source

Protease‐Activated Plasmonic Nanosensors for Predictive Ultrasound‐Guided Photoacoustic Imaging of Tumor Responses to Adoptive T Cell Therapy

Advanced Science, EarlyView.
Protease‐activated plasmonic nanosensors are demonstrated to noninvasively monitor antitumor T cell activity in tumors with anatomical information upon adoptive T cell transfer via ultrasound‐guided photoacoustic imaging. These nanosensors are actuated by granzyme B, a protease secreted by activated cytotoxic T cells during tumor cell killing, which ...
Myeongsoo Kim, Seoyoon Song, Ali Zamat, Paul S. Pelkowski, Shivashankar Subramanian, Melissa Cadena, Sydney Fabrega, Meredith Brienen, Jinhwan Kim, Gabriel A. Kwong, Stanislav Y. Emelianov   +10 more
wiley   +1 more source

Identifying active vascular microcalcification by 18F-sodium fluoride positron emission tomography

Nature Communications, 2015
Vascular calcification is a complex biological process that is a hallmark of atherosclerosis. While macrocalcification confers plaque stability, microcalcification is a key feature of high-risk atheroma and is associated with increased morbidity and ...
Agnese Irkle, A. Vesey, David Y. Lewis, J. Skepper, Joseph L. E. Bird, M. Dweck, Francis R. Joshi, Ferdia A Gallagher, Elizabeth A. Warburton, Martin R. Bennett, Kevin M. Brindle, D. E. Newby, J. Rudd, Anthony P. Davenport   +13 more
semanticscholar   +1 more source

NIR Ratiometric Fluorescent Antibody‐Drug Conjugate for Metastatic Ovarian Cancer Theranostics and Treatment Response Monitoring

Advanced Science, EarlyView.
In vivo optical imaging enhances antibody‐drug conjugate (ADC) optimization by enabling real‐time monitoring of stimulus‐responsive drug behavior. We report n501‐CYMMAF, a ratiometric theranostic with strong target affinity and low‐dose efficacy for ovarian metastasis.
Cheng Li, Zezhong Yu, Tao Pu, Yanling Wu, Gang Wang, Youhua Xie, Tianlei Ying, Zhenlin Yang, Yibing Shi   +8 more
wiley   +1 more source

Correction to: The aluminium-[18F]fuoride revolution: simple radiochemistry with a big impact for radiolabelled biomolecules

EJNMMI Radiopharmacy and Chemistry, 2021
Stephen J. Archibald, Louis Allott
doaj   +1 more source

Randomized control trial of using tongue acupuncture in autism spectrum disorder

Journal of Traditional Chinese Medical Sciences, 2014
Objective: The therapeutic approach of traditional chinese Medicine (TCM) in autism spectrum disorder (ASD) is a functional one. To study the efficacy, safety and functional brain change from the use of tongue acupuncture (TAC) on ASD children.
Virginia Chun-Nei Wong, Jie-Guang Sun, David Wai-Chow Yeung   +2 more
doaj   +1 more source

Correction: Prospective study on the clinical relevance of 18F-DOPA positron emission tomography/computed tomography in patients with medullary thyroid carcinoma [PDF]

, 2022
Inés Califano, Fabián Pitoia, Roxana Chirico, Alejandra de Salazar, María Bastianello   +4 more
openalex   +1 more source