Results 71 to 80 of about 271,559 (315)
Radiosynthesis of [18F]-Labelled Pro-Nucleotides (ProTides)
Molecules, 2020 Phosphoramidate pro-nucleotides (ProTides) have revolutionized the field of anti-viral and anti-cancer nucleoside therapy, overcoming the major limitations of nucleoside therapies and achieving clinical and commercial success.
Alessandra Cavaliere +7 more
doaj +1 more source
Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs +7 more
wiley +1 more source
Quantifying lung growth with CT-derived intrapulmonary vascular volume: a cross-sectional study
BMC Medical ImagingBackground This study aimed to evaluate lung growth by the quantitative assessment of intrapulmonary vascular volume on chest CT images. Methods All 1122 subjects were grouped with a 2-year age span.
Meijuan Shi +6 more
doaj +1 more source
Development of new radiopharmaceutical for molecular imaging in oncology [PDF]
, 2011 De afgelopen jaren zijn diverse nieuwe geneesmiddelen tegen kanker ontwikkeld. Er kan echter nog niet goed vooraf voorspeld worden bij welke patiënt deze nieuwe geneesmiddelen zullen werken.
Dijkers, Eli Carl Ferre, +1 more
core
, 2011 OBJECTIVES: 18F-Fluorodeoxyglucose positron emission tomography can detect cervical metastases before they are palpable. However, false positive results are not uncommon. This paper reports the use of ultrasound-guided fine needle aspiration to determine
王成平;李仲毅;婁培人;顏若芳;蕭仲凱;柯政郁 +1 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie +8 more
wiley +1 more source
Smoothing dynamic positron emission tomography time courses using functional principal components [PDF]
, 2009 A functional smoothing approach to the analysis of PET time course data is presented. By borrowing information across space and accounting for this pooling through the use of a nonparametric covariate adjustment, it is possible to smooth the PET time ...
Aston, John A. D. +2 more
core
Is there a role for fluorine 18 fluorodeoxyglucose-positron emission tomography and positron emission tomography/computed tomography in evaluating patients with mycobacteriosis? A systematic review [PDF]
, 2011 This study was designed to review the emerging role of fluorine 18 fluorodeoxyglucose (18F-FDG)-positron emission tomography (PET) CT/computed tomography (PET/CT) in patients with ...
Bonomo, Lorenzo +11 more
core +1 more source
Arthritis Care &Research, EarlyView.Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos +2 more
wiley +1 more source
Journal of Lipid Research, 2009 Docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), long-chain n-3 PUFAs important for brain and heart function, can be obtained from dietary fish products or by liver synthesis from α-linolenic acid (α-LNA).
Fei Gao +6 more
doaj +1 more source