Results 101 to 110 of about 283,504 (300)

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

The PROMISE-V2 PRIMARY score and SULmax [18F]PSMA-1007 PET/CT in primary staging of prostate cancer

Journal of the Mexican Federation of Radiology and Imaging
Introduction: The PRIMARY score of the PROMISE-V2 criteria for primary staging of prostate cancer (PCa) and its relationship with the maximum standardized uptake value normalized to lean body mass (SULmax) have not been evaluated.
J. Antonio Serna-Macias, M. Lourdes Garcia-Colmenero, Emilly A. Cortes-Mancera, E. David Muñoz-Carpio, Mixel Z. Baltierra-Hernandez   +4 more
doaj   +1 more source

PET/CT en oncología pediátrica

Revista Médica Clínica Las Condes, 2011
Los exámenes metabólicos con PET (Positron Emission Tomography) han experimentado un notable desarrollo tecnológico y expansión de su uso clínico en las últimas décadas.
Dr. H. David Ladrón de Guevara
doaj   +1 more source

UPM miliki MRI 3 Tesla, pertama seumpamanya di Malaysia [PDF]

, 2015
SERDANG, 4 Jun (UPM) – Selepas menjadi universiti awam pertama di negara ini mempunyai kelengkapan PET-CT Scan (Positron Emission Tomography – Computed Tomography Scan) pada tahun 2010, Universiti Putra Malaysia (UPM) terus membuat langkahan besar ...
Universiti Putra Malaysia, Pejabat Strategi Korporat dan Komunikasi
core  

ACSL1‐Dependent Microglial Lipoimmunometabolic Reprogramming Underlies Cognitive Deficits in Alcohol Use Disorder

Advanced Science, EarlyView.
This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao, Xing‐Rui Cao, Bai‐Qiang Li, Fu‐Ying Zhao, Jia‐Mei Wang, Rui‐Kang Gao, Zhi‐Peng Cao, Zhen‐Xian Du, Hua‐Qin Wang   +8 more
wiley   +1 more source

The Role of FDG PET/CT in a Patient with Larynx Cancer Who Developed Necrotizing Fasciitis Secondary to Tracheostomy Which is a Rare Complication

Ankara Üniversitesi Tıp Fakültesi Mecmuası, 2017
Necrotizing fasciitis (NF) is characterized with rapid involvement of soft tissues and fascias and could be fatal if not treated properly. Our patient had history of larynx cancer.
Ebru Bayar, Gonca Bural
doaj   +1 more source

The application of positron emission tomography (PET/CT) in diagnosis of breast cancer. Part II. Diagnosis after treatment initiation, future perspectives

Contemporary Oncology, 2016
Similarly to the applications described in the first part of this publication, positron emission tomography with computed tomography (PET/CT) is also gaining importance in monitoring a tumour’s response to therapy and diagnosing breast cancer recurrences.
Elżbieta Jodłowska, Rafał Czepczyński, Agata Czarnywojtek, Amanda Rewers, Grażyna Jarząbek, Witold Kędzia, Marek Ruchała   +6 more
doaj   +1 more source

A Renal Clearable Probe for In Vivo Monoamine Oxidase (MAO) Detection

Advanced Science, EarlyView.
A renal‐clearable Cy7‐based fluorogenic probe enables rapid and non‐invasive detection of monoamine oxidase (MAO) activity in vivo. Upon MAO‐mediated activation, the fluorescent product is efficiently excreted in urine, allowing direct quantification of enzyme overexpression.
Marcia Domínguez, David Azorín‐Soriano, Araceli Lérida‐Viso, Jessie García‐Fleitas, Paula M Soriano‐Teruel, Jennifer Soler Beatty, Paula Rodrigo‐Martínez, Pau Arroyo, Sara Rojas‐Vázquez, Isabel Fariñas, Félix Sancenón, Juan F. Blandez, Alba García‐Fernández, Ramón Martínez‐Máñez   +13 more
wiley   +1 more source

Accumulation of Tau Protein, Metabolism and Perfusion—Application and Efficacy of Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) Imaging in the Examination of Progressive Supranuclear Palsy (PSP) and Corticobasal Syndrome (CBS)

Frontiers in Neurology, 2019
Neuroimaging in the context of examining atypical parkinsonian tauopathies is an evolving matter. Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) bring tools, which may be reasonable in supplementary examination,
Piotr Alster, Natalia Katarzyna Madetko, Dariusz Mariusz Koziorowski, Leszek Królicki, Sławomir Budrewicz, Andrzej Friedman   +5 more
doaj   +1 more source

Exploring the Vasculitis‐Tumors Link: Epidemiological Patterns, Mechanistic Insights, and Clinical Implications

Advanced Science, EarlyView.
This review outlines association between vasculitis and malignancies and provides practical value for clinicians in distinguishing primary vasculitis from malignancy‐associated forms and optimizing patient surveillance, improving recognition of tumor‐associated vasculitis to reduce the risk of misdiagnosis, supporting more accurate clinical decision ...
Xiaofei Shi, Zhijiao Li, Xin Ma, Bei Zhang, Xinfeng Wu, Hua Fan, Rongzeng Liu, Hongwei Jiang, Cong‐Qiu Chu   +8 more
wiley   +1 more source