Results 51 to 60 of about 7,117,019 (296)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Possibility of Language Theory in Saussurean Linguistic Model
Saussure's 'Course in General Linguistics', is a book dealing with a particular topic in the broader subject of 'Language'. It was compiled and put into book form, after his death, with the help of notes collected by his students from his lectures given ...
Imtiaz Hussain
doaj +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
A Possibilistic Formulation of Autonomous Search for Targets
Autonomous search is an ongoing cycle of sensing, statistical estimation, and motion control with the objective to find and localise targets in a designated search area.
Zhijin Chen, Branko Ristic, Du Yong Kim
doaj +1 more source
Possibility Puzzle from Speech Act Theory Perspective [PDF]
The aim of this paper is to analyze the „possibility puzzle” presented by Shapiro (2011) in the context of the debate between conventionalism and non-conventionalism in speech act theory.
Bartosz Biskup
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Wavefront Propagation and Fuzzy Based Autonomous Navigation
Path planning and obstacle avoidance are the two major issues in any navigation system. Wavefront propagation algorithm, as a good path planner, can be used to determine an optimal path.
Cindy Leung, Adel Al-Jumaily
doaj
Complete information on the component reliability of the complex man-machine systems is obtained in the case of availability of the component uptime distribution laws and of their parameters, as well as of the information on the components independence ...
Anastas Leonidovich Boran-Keshishyan
doaj +1 more source

