Results 71 to 80 of about 7,117,019 (296)
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Chemical Possibility and Modal Semantics [PDF]
In the course of their work, chemists sometimes judge particular chemical processes to be possible or impossible. In this note I examine the semantics of the notion of possibility implicit in these judgments.
Sharlow, Mark
core
The Possibilistic Mean-Variance Model with Uncertain Possibility Distributions
The possibilistic mean–variance (MV) model is the counterpart of Markowitz’s MV model in the possibility theory. This study aims to examine the possibilistic MV model when the possibility distributions of stock returns are uncertain triangular fuzzy ...
Furkan Göktaş
doaj +1 more source
Bounding probabilistic sea-level projections within the framework of the possibility theory
Despite progresses in climate change science, projections of future sea-level rise remain highly uncertain, especially due to large unknowns in the melting processes affecting the ice-sheets in Greenland and Antarctica.
Gonéri Le Cozannet +2 more
doaj +1 more source
IS NO DRAMA QUANTUM THEORY POSSIBLE? [PDF]
The matter field can be naturally eliminated from the equations of the Klein-Gordon-Maxwell electrodynamics in the unitary gauge. The resulting equations describe independent dynamics of the electromagnetic field: if components of the 4-potential of the electromagnetic field and their first derivatives with respect to time are known in the entire ...
openaire +2 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Possibility and permissibility [PDF]
We generalize permissibility (Brandenburger, 1992) to allow for any suitably defined model of preference and definition of possibility. We also prove that the generalized solution concept characterizes rationality, caution, and “common belief" of ...
Kin Chung Lo
core
Assessing landslide susceptibility by applying fuzzy sets, possibility evidence-based theories
A landslide susceptibility model was developed for the city of Manizales, Colombia; landslides have been the city’s main environmental problem. Fuzzy sets and possibility and evidence-based theories were used to construct the mo-del due to the set of ...
Ibsen Chivatá Cárdenas
doaj

