Results 81 to 90 of about 7,117,019 (296)
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
The possibility of knowledge [PDF]
, 2007 I focus on two questions: what is knowledge, and how is knowledge possible? The latter is an example of a how-possible question. I argue that how-possible questions are obstacle-dependent and that they need to be dealt with at three different levels, the
Cassam, Quassim, Quassim Cassam
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CAAI Transactions on Intelligence Technology, 2019 This study presented a multi-objective linear fractional inventory (LFI) problem with generalised intuitionistic fuzzy numbers. In modelling, the authors have assumed the ambiances where generalised trapezoidal intuitionistic fuzzy numbers (GTIFNs) used ...
Totan Garai, Harish Garg
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Possibility functions and regular economies [PDF]
In the spirit of Smale's work, we consider pure exchange economies with general consumption sets. In this paper, the consumption set of each household is described in terms of a function called possibility function.
Jean-Marc Bonnisseau +1 more
core
Sensors, 2012 This study proposes a new condition diagnosis method for rotating machinery developed using least squares mapping (LSM) and a fuzzy neural network. The non-dimensional symptom parameters (NSPs) in the time domain are defined to reflect the features of ...
Peng Chen, Shiming Wang, Ke Li
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
, 2018 Based upon long-term fieldwork among African American families in Los Angeles, this article offers a phenomenological investigation of the indeterminate structures of ethical experience. Drawing upon Waldenfels’ responsive phenomenology in the context of
Mattingly, Cheryl
core +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
GeosciencesSeismic hazards in Thailand are frequently overlooked in disaster management planning, leading to insufficient research and significant economic losses during earthquake events.
Patcharavadee Hong, Masashi Matsuoka
doaj +1 more source