Results 61 to 70 of about 7,117,019 (296)

Possibility theory for multiobjective fuzzy random portfolio optimization [PDF]

Decision Science Letters, 2014
The problem of portfolio optimization is a standard problem in financial world and it has received tremendous attentions. Portfolio optimization plays essential role in determining portfolio strategies for investors.
Mir Ehsan Hesam Sadati, Ali Doniavi, Abbas Samadi   +2 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Linguistically Defined Clustering of Data

International Journal of Applied Mathematics and Computer Science, 2018
This paper introduces a method of data clustering that is based on linguistically specified rules, similar to those applied by a human visually fulfilling a task. The method endeavors to follow these remarkable capabilities of intelligent beings.
Leski Jacek M., Kotas Marian P.
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

A possible theory of weak interactions [PDF]

Nuclear Physics, 1958
Abstract A discussion is given of some of the recent experimental results in β-decay, and a possible theory of weak interactions is presented which is able to reproduce most of the results of the two-component theory but allows for the simultaneous presence of S and V in β-interaction without violating time reversal.
openaire   +2 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

A Maximal Covering Location Problem Under Uncertainty Through Possibility Theory

Mathematics
This study presents a practical framework for the maximal covering location problem (MCLP) under uncertainty. The approach combines possibility theory with chance-constrained programming to represent both imprecision and randomness in demand.
Javad Nematian, Predrag S. Stanimirović, Shahryar Ghorbani, Darjan Karabašević, Pavle Brzaković   +4 more
doaj   +1 more source

The Possibilities of Theory - the Theory of Possibilities

Przestrzenie Teorii
This essay attempts to describe a new field of research in contemporary literary theory, defined in terms of performative, dramatic, and dramaturgical interactions and relations. The focus is placed on the dynamic movement of concepts and categories, as it allows theory to keep up with the constant new developments in literature and culture.
openaire   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source