Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
The effect of augmented feedback with velocity-based training on post-activation performance enhancement in college soccer players. [PDF]
Zhao Z +5 more
europepmc +1 more source
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Time-course of post-activation performance enhancement (PAPE) following multi-dimensional elastic band vs. heavy resistance exercise. [PDF]
Liu Y, Zou X, Lu D, Xu N, Chen M, Zhu L.
europepmc +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Acute effects of French contrast and post-activation performance enhancement on throwing, jump performance, and training load in handball players. [PDF]
Eler N +5 more
europepmc +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Effects of caffeinated gum doses combined with post-activation performance enhancement on bench-press bar velocity: a randomized crossover study. [PDF]
Wang Z +9 more
europepmc +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Post-Activation Performance Enhancement in soccer: A Systematic Review of the Effects of Resistance and Plyometric Training Methods [PDF]
Název: Postaktivační zvýšení výkonu ve fotbale: Systematická rešerše vlivu odporových a plyometrických tréninkových metod Cíle: Cílem této systematické rešerše bylo analyzovat vliv postaktivační potenciace (PAPE) a primingu, vyvolaného odporovým nebo ...
Čunát, Martin
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