Results 91 to 100 of about 5,534,109 (312)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Post-conflict aid, real exchange rate adjustment, and catch-up growth [PDF]
Post-conflict countries receive substantial aid flows after the start of peace. While post-conflict countries'capacity to absorb aid (that is, the quality of their policies and institutions) is built up only gradually after the onset of peace, the ...
Elbadawi, Ibrahim A. +2 more
core
Post-Conflict Peace Construction in Somaliland
Journal of Central and Eastern European African StudiesThe Horn of African region has witnessed a prolonged conflict, and Somaliland has grabbed its share. This article explores and finds answers for the questions related with the blockage factors of post-conflict peace construction in Somaliland, analyses ...
Abdalgani Almi
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Exchange Rate and Monetary Policy for Sustainable Post-conflict Transition [PDF]
This paper asks the question as to whether the choice of the exchange rate regime matters for post-conflict economic recovery and macro stabilization. Though an important aspect of the macroeconomic agenda for post-conflict, it has however, been largely ...
Raimundo Soto, Ibrahim Elbadawi
core
The role of self-perception in mental health: current insights on self-esteem and self-schemas
Frontiers in PsychiatryBackgroundSelf perception includes both self-esteem and self-schema and is an important factor in determining an individual's mental health. This is particularly true in contexts that have been affected by war or conflict, such as post-conflict Mosul ...
Radhwan Hussein Ibrahim +4 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Post-conflict behaviour of spectacled Langurs (Trachypithecus obscurus) [PDF]
, 1997 Studies of post-conflict behaviour in primates have two aims, 1) to uncover the fundamental mechanisms underlying conflict resolution, 2) to integrate patterns of reconciliation within broad models of socio-ecology.
Arnold, Kate
core
International Review of the Red CrossOver a decade of conflict has ruptured protective layers for children, adolescents and caregivers in Syria, resulting in heightened mental health and psychosocial support (MHPSS) needs.
Jihad Taha +4 more
doaj +1 more source