Results 81 to 90 of about 2,841,334 (307)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The Property Tax as a Tax on Value: Deadweight Loss [PDF]
Consider an atomistic developer who decides when and at what density to develop his land, under a property tax system characterized by three time-invariant tax rates: the tax rate on pre-development land value, the tax rate on post-development residual ...
Petia Petrova, Richard Arnott
core
Town of New Durham Stormwater Management & Erosion Control Project [PDF]
, 2010 Appledore Engineering worked with the New Durham Planning Board to develop a stormwater management and erosion control ordinance and to adopt complimentary improvements to the town’s site plan review and subdivision ...
Town of Durham
core +2 more sources
, 2020 Quantum bits, or qubits, are an example of coherent circuits envisioned for next-generation computers and detectors. A robust superconducting qubit with a coherent lifetime of $O$(100 $\mu$s) is the transmon: a Josephson junction functioning as a non ...
Kreikebaum, J. M. +3 more
core +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Land Development in Emerging Markets [PDF]
One of the most important issues in emerging markets is the timing and intensity of land development decisions and how these decisions affect property values.
Yuming Li
core
Town of Newington Stormwater Management Project [PDF]
, 2010 The UNH Stormwater Center worked with the Newington Planning Board to improve the town’s site plan review regulations to better manage ...
Town of Newington
core +2 more sources
Tropical Cyclone Intensity Estimation Using Multi-Dimensional Convolutional Neural Networks from Geostationary Satellite Data [PDF]
, 2019 For a long time, researchers have tried to find a way to analyze tropical cyclone (TC) intensity in real-time. Since there is no standardized method for estimating TC intensity and the most widely used method is a manual algorithm using satellite-based ...
Amit +21 more
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Trapping/Pinning of colloidal microspheres over glass substrate using surface features
, 2017 Suspensions of micro and nano particles made of Polystyrene, Poly(methyl methacrylate), Silicon dioxide etc. have been a standard model system to understand colloidal physics. .
Prakash, Praneet, Varma, Manoj
core +2 more sources