Results 121 to 130 of about 129,838 (326)

Biomimetic Organic Nanozyme as Tumor Vaccines for Targeted Suppression of Ammonia‐Induced T Lymphocyte Death to Augment Breast Cancer Immunotherapy

Advanced Science, EarlyView.
The organic nanozyme IR‐IHpd, which has NIR‐PDT and POD‐like activity, is designed for continuous ROS generation. It is co‐encapsulated with CB‐839 and coated with DC membranes to simultaneously target tumors and T cells. Under NIR irradiation, immunogenic cell death is activated. Concurrently, CB‐839 suppresses ammonia‐induced T lymphocyte death (AITD)
Meng Suo, Deyi Yang, Mingpu Yang, Jue Wang, Dingfeng Zhang, Daoming Zhu, Qingyong Xu, Yanni Song   +7 more
wiley   +1 more source

Clinical and epidemiological profile of patients who seek post-exposure prophylaxis after sexual exposure to HIV and their adherence to the medication regimen in a specialized center in Cascavel, Paraná, Brazil

DST, 2019
Introduction: Post-Exposure Prophylaxis (PEP) is part of a new strategy for the prevention of Human Immunodeficiency Virus transmission adopted by the Brazilian Ministry of Health.
Vania Orlandi, Dilson Fronza, Douglas Soltau Gomes, Josana Aparecida Dranka Horvath, Winny Hirome Takahashi Yonegura   +4 more
doaj  

1528Ralteragir Containing regimen, for Post Exposure Prophylaxis (PEP), well tolerated in Health Care Workers (HCW) [PDF]

, 2014
Kassem Bourgi, Daniela Thompson, Dwayne Baxa, Indira Brar   +3 more
openalex   +1 more source

Phocaeicola coprophilus‐Derived 6‐Methyluracil Attenuates Radiation‐Induced Intestinal Fibrosis by Suppressing the IDO1‐Kynurenine‐AHR Axis

Advanced Science, EarlyView.
IR‐induced dysbiosis depletes P. coprophilus and its metabolite 6‐methyluracil, leading to disinhibition of the IDO1‐Kyn‐AHR axis. This results in sustained fibroblast activation and collagen deposition, driving radiation induced intestinal fibrosis. ABSTRACT Therapeutic options for radiation‐induced intestinal fibrosis (RIF) remain limited. This study
Jiaxin Zhang, Zhen Wang, Shuang Li, Chao Luo, Han Li, Shengjie Ma, Pai Wang, Heshi Liu, Lijun Sun, Yue Yin, Weizhen Zhang, Quan Wang   +11 more
wiley   +1 more source

Emergent informal use of doxycycline post- and pre-exposure prophylaxis among men who have sex with men and transgender and gender diverse people, the Netherlands, 2024

Eurosurveillance
BACKGROUND Doxycycline post-exposure and pre-exposure prophylaxis (doxyPEP/PrEP) to prevent sexually transmitted infections (STIs) is not part of standard practice in the Netherlands but may be used informally (without prescription).
Vita W Jongen
doaj   +1 more source

Predictors and Highlights for pre- and post-exposure Prophylaxis Uptake among Men who have sex with Men in three large Cities in China [PDF]

, 2022
Xiaofang Wang, Jie Li, Lijun Sun, An Liu, Yanping Yu, Chongxi Li, Tianjun Jiang, Bin Song, Xiaoning Liu, Jun Liu   +9 more
openalex   +1 more source

Outcomes of Pancreas‐Sparing Total Duodenectomy for Severe Duodenal Polyposis in Patients With Familial Adenomatous Polyposis

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim Spigelman stage IV duodenal polyposis (SP‐stage IV DP) is associated with high duodenal cancer risk in patients with familial adenomatous polyposis (FAP). This study evaluated the surgical and oncological outcomes of pancreas‐sparing total duodenectomy (PSTD) as a surgical prophylaxis for severe duodenal polyposis in FAP.
Takehiro Shiraishi, Hideyuki Ishida, Takatoshi Matsuyama, Noriyasu Chika, Yoshiko Mori, Norimichi Chiyonobu, Youichi Kumagai, Ibuki Fujinuma, Toshiro Ogura   +8 more
wiley   +1 more source

Enhancing Human Post‐Exposure Rabies Prophylaxis in Canine Rabies Endemic Regions With an Interactive Web Solution

Public Health Challenges
Despite the availability of effective biologics, rabies continues to impact several low‐ and middle‐income countries. More than 50,000 people succumb to rabies every year due to the lack of timely and appropriate post‐bite care.
Aniruddha V. Belsare, Deborah J. Briggs, Gyanendra Gongal, Reeta S. Mani, Charles E. Rupprecht   +4 more
doaj   +1 more source

Evidence-Based Study of Medication Compliance Project in Hiv Prevention Using Pre-Exposure Prophylaxis (Prep) Antivirals for HIV-Negative Males [PDF]

, 2018
In 2012, emtricitabine/tenofovir was the only Food and Drug Administration-approved medication for pre-exposure prophylaxis (PrEP) used in human immunodeficiency virus (HIV) prevention.
Ho, Ming-Chun
core   +1 more source

Rabies encephalitis in a child: a failure of rabies post exposure prophylaxis? [PDF]

, 2015
Faten Tinsa, Aida Borgi, Imen Jahouat, Khadija Boussetta   +3 more
openalex   +1 more source