Results 131 to 140 of about 129,838 (326)

Factor XIII Supplementation in Postpartum Hemorrhage: From Biological Rationale to Clinical Implementation

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Postpartum hemorrhage (PPH) remains the leading cause of preventable maternal mortality despite standard interventions. Recent fibrinogen trials failed to improve outcomes, prompting interest in coagulation factor XIII (FXIII). FXIII functions as “molecular cement,” cross‐linking fibrin and stabilizing clots.
Jeremy W. Jacobs   +8 more
wiley   +1 more source

Occupational post-exposure HIV prophylaxis.

open access: yesSouth African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2004
HIV and other bloodborne infectious agents, such as hepatitis B or C, can be transmitted to health care workers during occupational exposure. In all occupational exposure incidents proper documentation is essential in order to claim compensation at a later date.
openaire   +2 more sources

Biocompatibility and healing patterns in experimentally induced canine tibial fractures using Pedicle screw‐Rod external fixation

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study demonstrates that using a Pedicle screw‐Rod configuration for the external fixation of non‐articular tibial osteotomy aligns well with the principles of biological osteosynthesis, resulting in secondary bone healing characterized by callus formation and neovascularization.
Mohammad Mahdi Gooran   +3 more
wiley   +1 more source

Major Causes of Rabies Outbreak in Pastoral Areas of the Somali Region and Importance of the One Health Approach

open access: yesAnimal Research and One Health, EarlyView.
Rabies Transmission and Control in the Somali Region. Introduction: Rabies is a fatal zoonotic disease caused by the Lyssavirus, posing a significant threat to both wildlife and public health in the Somali Region of Ethiopia. Key Points: 1. Primary Hosts: Wild carnivores such as foxes, jackals, raccoons, skunks, bats, and honey badgers are the main ...
Hassan Abdi Hussein
wiley   +1 more source

Case‐Based Immunology: B Cells and Systemic Sclerosis Interstitial Lung Disease

open access: yesArthritis &Rheumatology, EarlyView.
Interstitial lung disease (ILD) is an important complication of systemic sclerosis (SSc), with high mortality and morbidity. Recent clinical studies in SSc‐ILD have led to US Food and Drug Administration–approved therapies in SSc‐ILD. Importantly, evidence from these studies has been extrapolated to guide management of ILDs of other systemic autoimmune
Nina Goldman   +2 more
wiley   +1 more source

A real‐world data‐driven approach to optimizing enoxaparin dosing in burn patients

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Enoxaparin dosing in burn patients is challenging due to physiological changes affecting absorption, distribution and clearance. The objectives of this study are to develop a population pharmacokinetic (PK) model for enoxaparin in burn patients, evaluate target attainment with current equation‐based (EQ) dosing and propose an optimized dosing ...
Babajide Shenkoya   +3 more
wiley   +1 more source

Population pharmacokinetics of levofloxacin in breastmilk in patients with rifampicin‐resistant tuberculosis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Levofloxacin is a widely used antibiotic included in rifampicin‐resistant tuberculosis (RR‐TB) treatment. Data describing levofloxacin concentrations in breastmilk and infant exposure are limited. We analysed data from two South African studies of breastfeeding women receiving levofloxacin (750–1000 mg daily) for RR‐TB.
Sharon Sawe   +9 more
wiley   +1 more source

Comparative Efficacy of Pre and Post-Exposure Pro-Phylaxis Using Local Rabies Vaccine by IM Route

open access: yesTSF Journal of Biology
Rabies is an infectious but preventable disease with proper vaccination. Pre-exposure prophylaxis means using medications or vaccines against a given pathogen in people who have not yet been exposed to the given pathogen. Post-exposure prophylaxis means
Kaneez Fatima   +5 more
doaj   +1 more source

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