Results 71 to 80 of about 6,476,358 (258)

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

open access: yesAdvanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang   +11 more
wiley   +1 more source

Predictors of linkage to prevention services after HIV post-exposure prophylaxis (PEP): A single-centre retrospective analysis, years 2019-2024

open access: yesInternational Journal of Infectious Diseases
Objectives: Post-exposure prophylaxis (PEP) remains underutilised and real-world data on its role within prevention pathways are limited.We aimed to describe PEP use following sexual exposure and to identify predictors of linkage to prevention services ...
Rozenn Esvan   +13 more
doaj   +1 more source

How familiar are our doctors towards Rabies prophylaxis- A study from coastal south India.

open access: yesPLoS Neglected Tropical Diseases, 2017
BackgroundRabies, a 100% fatal disease claims more than 59,000 human lives every year globally. One human life is lost every 15 minutes due to this deadly preventable disease.
Ramesh Holla   +9 more
doaj   +1 more source

Intelligent Programmable Membrane Nanosponge for Early Virus Blocking

open access: yesAdvanced Science, EarlyView.
A smart programmable nanosponge (ACNPs) displays high‐density viral receptors on its membrane and encapsulates fusion inhibitors to capture virions at the infection source through competitive binding and blocks their entry through protease inhibition for ultra‐early cascade interception. This modular, mucus‐penetrating platform shifts antiviral defence
Ze Chen   +17 more
wiley   +1 more source

Awareness and attitude of nigerian dentists to occupational HIV post-exposure prophylaxis

open access: yesSahel Medical Journal, 2010
Background: The incidence of human immunodeficiency virus infection in Nigeria remains worrisome. Dentists are increasingly becoming at risk of occupational exposure to the virus.
Sunny A Okeigbemen, Alice A Umweni
doaj  

Abstract Representation of Movement Parameters in Basal Ganglia Output

open access: yesAdvanced Science, EarlyView.
The basal ganglia output provides a scalable velocity/position signal across behavioral contexts, supporting the idea that these variables are represented in the brain as abstract entities rather than as fixed changes in joint angles or specific sets of body effectors.
Ana Silvia Báez‐Cordero   +3 more
wiley   +1 more source

A Study on Delay in Initiation of Post-exposure Prophylaxis among the Animal Bite Victims from a Tertiary Care Hospital in Central India

open access: yesIndian Journal of Community Medicine
Context: Rabies is a viral zoonotic disease associated with various sociocultural practices and myths, leading to ineffective and timely initiation of post-exposure prophylaxis (PEP) for wound management due to animal bite among the victims.
Arindam Maiti   +4 more
doaj   +1 more source

Supramolecular Zinc–Polyphenol Coordination Assemblies Mitigate Colonic Inflammation by Regulating Mucosal Barrier and Microbiome

open access: yesAdvanced Science, EarlyView.
A carrier‐free zinc‐coordinated polyphenol nanoplatform (ZnCA NPs) is designed as an “all‐in‐one” therapeutic strategy for intestinal inflammation. The ZnCA NPs exhibit enhanced colonic accumulation and broad‐spectrum reactive oxygen and nitrogen species scavenging.
Qiwen Xie   +7 more
wiley   +1 more source

Rabies: An overview

open access: yesInternational Journal of Advanced Medical and Health Research, 2014
Rabies is a fatal disease caused by rabies virus, a neurotropic virus and a prototype of Lyssavirus of Rhabdoviridae family. It is transmitted to human beings through infected saliva of dogs and cats during bite.
Tarun Kumar Dutta
doaj   +1 more source

HIV pre-exposure prophylaxis : statewide plan and guidance

open access: yes, 2022
The South Carolina Department of Health and Environmental Control (DHEC) HIV Pre-exposure Prophylaxis (PrEP) Statewide Plan and Guidance has been developed by DHEC as an element of the PrEPMeSC initiative.
Department of Health and Environmental Control. Division of STD/HIV and Viral Hepatitis
core  

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